ENSDARG00000062221


Danio rerio

Features
Gene ID: ENSDARG00000062221
  
Biological name :si:ch211-135f11.1
  
Synonyms : si:ch211-135f11.1
  
Possible biological names infered from orthology : ARAP1 / Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 / Q4LDD4 / Q96P48
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 23888314
Gene end: 23909934
  
Corresponding Affymetrix probe sets: Dr.24018.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000123586
swissprot - A0A0A0MPV6
ZFIN ID - ZDB-GENE-030131-6226
Ensembl - ENSDARG00000062221
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARAP1ENSG00000186635Homo sapiens
 Arap1ENSMUSG00000032812Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arap3 / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 / Q8R5G7* / Q8WWN8* / Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 *ENSDARG0000007680133
CR387919.1 / ARAP2* / Q8WZ64* / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2*ENSDARG0000010051833
FO704810.1ENSDARG0000008749222
arhgap35a / Rho GTPase activating protein 35a / Q91YM2* / Q9NRY4* / ARHGAP35* / Rho GTPase activating protein 35*ENSDARG0000006257712
arhgap35b / Rho GTPase activating protein 35b / Q91YM2* / Q9NRY4* / ARHGAP35* / Rho GTPase activating protein 35*ENSDARG0000006029711
arhgap5 / Rho GTPase activating protein 5 / Q13017*ENSDARG0000006129411


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001164  Arf GTPase activating protein
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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