ENSDARG00000076801


Danio rerio

Features
Gene ID: ENSDARG00000076801
  
Biological name :arap3
  
Synonyms : arap3 / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
  
Possible biological names infered from orthology : Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 / Q8R5G7 / Q8WWN8
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 26566936
Gene end: 26626130
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000142557
NCBI entrez gene - 558931     See in Manteia.
RefSeq - XM_005173181
RefSeq - XM_682220
swissprot - A0A140LH27
ZFIN ID - ZDB-GENE-091019-1
Ensembl - ENSDARG00000076801
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARAP3ENSGALG00000002562Gallus gallus
 ARAP3ENSG00000120318Homo sapiens
 Arap3ENSMUSG00000024451Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CR387919.1 / ARAP2* / Q8WZ64* / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2*ENSDARG0000010051831
si:ch211-135f11.1 / ARAP1* / Q4LDD4* / Q96P48* / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1* / Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 *ENSDARG0000006222120
FO704810.1ENSDARG0000008749214
arhgap35b / Rho GTPase activating protein 35b / Q91YM2* / Q9NRY4* / ARHGAP35* / Rho GTPase activating protein 35*ENSDARG0000006029711
arhgap35a / Rho GTPase activating protein 35a / Q91YM2* / Q9NRY4* / ARHGAP35* / Rho GTPase activating protein 35*ENSDARG0000006257711
arhgap5 / Rho GTPase activating protein 5 / Q13017*ENSDARG0000006129410


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000198  Rho GTPase-activating protein domain
 IPR001164  Arf GTPase activating protein
 IPR001660  Sterile alpha motif domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001946 lymphangiogenesis IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk edematous , abnormal
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 ZFA:0000671 horizontal myoseptum horizontal myoseptum has fewer parts of type vascular lymphangioblast , abnormal
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 ZFA:0005110 thoracic duct thoracic duct hypoplastic , abnormal
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 ZFA:0009395 vascular lymphangioblast vascular lymphangioblast hypoplastic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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