ENSDARG00000062472


Danio rerio

Features
Gene ID: ENSDARG00000062472
  
Biological name :sin3b
  
Synonyms : sin3b / SIN3 transcription regulator family member B
  
Possible biological names infered from orthology : O75182 / Q62141 / transcriptional regulator, SIN3B (yeast)
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 14211746
Gene end: 14239023
  
Corresponding Affymetrix probe sets: Dr.16431.1.S1_at (Zebrafish Array)   Dr.8569.1.A1_at (Zebrafish Array)   NM_001044945_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000084804
NCBI entrez gene - 560837     See in Manteia.
RefSeq - NM_001044945
RefSeq Peptide - NP_001038410
swissprot - Q1LYM8
ZFIN ID - ZDB-GENE-030131-8264
Ensembl - ENSDARG00000062472
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SIN3BENSGALG00000003771Gallus gallus
 SIN3BENSG00000127511Homo sapiens
 Sin3bENSMUSG00000031622Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sin3ab / SIN3 transcription regulator family member Ab / SIN3A* / Q96ST3* / Q60520* / SIN3 transcription regulator family member A* / Mus musculus transcriptional regulator, SIN3A (yeast) (...ENSDARG0000005981252
sin3aa / SIN3 transcription regulator family member Aa / SIN3A* / Q96ST3* / Q60520* / SIN3 transcription regulator family member A* / Mus musculus transcriptional regulator, SIN3A (yeast) (...ENSDARG0000007971652


Protein motifs (from Interpro)
Interpro ID Name
 IPR003822  Paired amphipathic helix
 IPR013194  Histone deacetylase interacting domain
 IPR031693  Sin3, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016575 histone deacetylation IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016580 Sin3 complex IBA
 molecular_functionGO:0004407 histone deacetylase activity IBA


Pathways (from Reactome)
Pathway description
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord ossification process quality , abnormal
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 ZFA:0001094 whole organism whole organism decreased speed , abnormal
whole organism decreased behavioural activity , abnormal
whole organism swimming decreased duration , abnormal
whole organism decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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