ENSDARG00000062640


Danio rerio

Features
Gene ID: ENSDARG00000062640
  
Biological name :kcnh8
  
Synonyms : kcnh8 / potassium voltage-gated channel, subfamily H (eag-related), member 8
  
Possible biological names infered from orthology : potassium voltage-gated channel subfamily H member 8 / Q96L42
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 20495249
Gene end: 20645531
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000085243
Ensembl peptide - ENSDARP00000157389
swissprot - F1QTV6
ZFIN ID - ZDB-GENE-060503-204
Ensembl - ENSDARG00000062640
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNH8ENSGALG00000011262Gallus gallus
 KCNH8ENSG00000183960Homo sapiens
 Kcnh8ENSMUSG00000035580Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kcnh4a / potassium voltage-gated channel, subfamily H (eag-related), member 4a / KCNH4* / Q9UQ05* / potassium voltage-gated channel subfamily H member 4*ENSDARG0000006256554
kcnh4b / potassium voltage-gated channel, subfamily H (eag-related), member 4b / KCNH4* / Q9UQ05* / potassium voltage-gated channel subfamily H member 4*ENSDARG0000006199053
kcnh3 / potassium voltage-gated channel, subfamily H (eag-related), member 3 / Q9ULD8* / Q9WVJ0* / potassium voltage-gated channel subfamily H member 3*ENSDARG0000006956052
kcnh6a / potassium voltage-gated channel, subfamily H (eag-related), member 6a / KCNH6* / KCNH7* / Q9NS40* / Q9ER47* / Q9H252* / potassium voltage-gated channel subfamily H member 6* / pota...ENSDARG0000000180333
kcnh2a / potassium voltage-gated channel, subfamily H (eag-related), member 2a / KCNH2* / Q12809* / potassium voltage-gated channel subfamily H member 2*ENSDARG0000002988133
kcnh7 / potassium channel, voltage gated eag related subfamily H, member 7ENSDARG0000006268733
kcnh1a / kcnh1b / potassium voltage-gated channel, subfamily H (eag-related), member 1a / KCNH1* / O95259* / AC092017.3* / AL590132.1* / potassium voltage-gated channel subfamily H member 1*ENSDARG0000002323629
kcnh1a / potassium voltage-gated channel, subfamily H (eag-related), member 1a / KCNH1* / O95259* / AC092017.3* / AL590132.1* / potassium voltage-gated channel subfamily H member 1*ENSDARG0000002416729
kcnh5a / potassium voltage-gated channel, subfamily H (eag-related), member 5a / KCNH5* / Q8NCM2* / Q920E3* / potassium voltage-gated channel subfamily H member 5*ENSDARG0000004322029
kcnh5b / potassium voltage-gated channel, subfamily H (eag-related), member 5bENSDARG0000006911729
kcnh6b / potassium voltage-gated channel, subfamily H (eag-related), member 6b / KCNH6* / KCNH7* / Q9NS40* / Q9ER47* / Q9H252* / potassium voltage-gated channel subfamily H member 6* / pota...ENSDARG0000001029624
CABZ01076968.1 / KCNH2* / Q12809* / potassium voltage-gated channel subfamily H member 2*ENSDARG0000010647324
cngk / cyclic nucleotide-gated potassium channelENSDARG0000009326715


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR000595  Cyclic nucleotide-binding domain
 IPR000700  PAS-associated, C-terminal
 IPR001610  PAC motif
 IPR003938  Potassium channel, voltage-dependent, EAG/ELK/ERG
 IPR003950  Potassium channel, voltage-dependent, ELK
 IPR005821  Ion transport domain
 IPR014710  RmlC-like jelly roll fold
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000160 phosphorelay signal transduction system IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000155 phosphorelay sensor kinase activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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