ENSDARG00000062745


Danio rerio

Features
Gene ID: ENSDARG00000062745
  
Biological name :socs5b
  
Synonyms : socs5b / suppressor of cytokine signaling 5b
  
Possible biological names infered from orthology : O54928 / O75159 / SOCS5 / suppressor of cytokine signaling 5
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 8604710
Gene end: 8628038
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000085530
swissprot - B0EVP6
ZFIN ID - ZDB-GENE-080722-18
Ensembl - ENSDARG00000062745
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOCS5ENSGALG00000010016Gallus gallus
 SOCS5ENSG00000171150Homo sapiens
 Socs5ENSMUSG00000037104Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
socs5a / suppressor of cytokine signaling 5a / SOCS5* / O75159* / O54928* / suppressor of cytokine signaling 5*ENSDARG0000010071762
socs9 / suppressor of cytokine signaling 9ENSDARG0000010198541
socs4 / suppressor of cytokine signaling 4ENSDARG0000007850930
socs6a / suppressor of cytokine signaling 6a / SOCS6* / O14544* / suppressor of cytokine signaling 6*ENSDARG0000005856518
socs6b / suppressor of cytokine signaling 6bENSDARG0000001586317
socs7 / suppressor of cytokine signaling 7 / O14512*ENSDARG0000007701816
cishb / cytokine inducible SH2-containing protein b / CISH* / Q62225* / Q9NSE2* / cytokine inducible SH2 containing protein*ENSDARG0000001677310
socs2 / suppressor of cytokine signaling 2 / O14508* / O35717*ENSDARG0000004555710
socs3a / suppressor of cytokine signaling 3a / SOCS3* / O14543* / suppressor of cytokine signaling 3*ENSDARG000000254289
socs3b / suppressor of cytokine signaling 3b / SOCS3* / O35718* / O14543* / suppressor of cytokine signaling 3*ENSDARG000000266119
socs1a / suppressor of cytokine signaling 1a / SOCS1* / O35716* / O15524* / suppressor of cytokine signaling 1*ENSDARG000000380959
cish / cytokine inducible SH2-containing protein / Q62225* / Q9NSE2*ENSDARG000000603169
socs1b / suppressor of cytokine signaling 1bENSDARG000000898739


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001496  SOCS box domain
 IPR022252  SOCS4/SOCS5 domain
 IPR028420  Suppressor of cytokine signalling 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0007259 JAK-STAT cascade IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr