ENSDARG00000062892


Danio rerio

Features
Gene ID: ENSDARG00000062892
  
Biological name :foxe3
  
Synonyms : forkhead box E3 / foxe3
  
Possible biological names infered from orthology : forkhead box E1 / Forkhead box protein E1 / Forkhead box protein E3 / FOXE1 / O00358 / Q13461 / Q8R2I0 / Q9QY14
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 19668654
Gene end: 19670305
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000085869
NCBI entrez gene - 570855     See in Manteia.
RefSeq - NM_001079682
RefSeq Peptide - NP_001073150
swissprot - B0UXI3
ZFIN ID - ZDB-GENE-061214-6
Ensembl - ENSDARG00000062892
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000028153Gallus gallus
 FOXE1ENSG00000178919Homo sapiens
 FOXE3ENSG00000186790Homo sapiens
 Foxe1ENSMUSG00000070990Mus musculus
 Foxe3ENSMUSG00000044518Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
foxe1 / forkhead box E1 / FOXE3* / Q9QY14* / O00358* / Q13461* / Q8R2I0* / forkhead box E3* / Forkhead box protein E3 * / Forkhead box protein E1 *ENSDARG0000007926632
foxd3 / forkhead box D3 / FOXD4* / Q9UJU5* / Q12950* / Q3SYB3* / Q5VV16* / Q60688* / Q6VB84* / Q8WXT5* / Q9NU39* / FOXD4L3* / FOXD4L4* / FOXD4L5* / FOXD4L6* / FOXD4L1* / forkhead box D4* / ...ENSDARG0000002103226
foxd1 / forkhead box D1 / FOXD2* / Q61345* / O35392* / O60548* / Q16676* / forkhead box D2* / Forkhead box protein D2 * / Forkhead box protein D1 *ENSDARG0000002917925
foxd2 / forkhead box D2 / FOXD1* / O35392* / O60548* / Q16676* / Q61345* / forkhead box D1* / Forkhead box protein D1 * / Forkhead box protein D2 *ENSDARG0000005813325
foxd5 / forkhead box D5 / FOXD1* / FOXD2* / Q16676* / Q61345* / O35392* / O60548* / forkhead box D2* / forkhead box D1* / Forkhead box protein D1 * / Forkhead box protein D2 *ENSDARG0000004248522
foxg1a / forkhead box G1a / FOXG1* / P55316* / Q60987* / Gm43517* / forkhead box G1* / Forkhead box protein G1 *ENSDARG0000007076921
zgc:162612 / FOXD1* / FOXD2* / O60548* / Q61345* / Q16676* / O35392* / forkhead box D1* / forkhead box D2* / Forkhead box protein D1 * / Forkhead box protein D2 *ENSDARG0000007969921
foxf1 / A1L1S5 / forkhead box F1 / Q61080* / Q12946* / Forkhead box protein F1 *ENSDARG0000001539920
foxg1b / forkhead box G1bENSDARG0000003270520
foxf2b / forkhead box F2b / FOXF2* / O54743* / Q12947* / forkhead box F2* / Forkhead box protein F2 *ENSDARG0000007038920
foxf2a / forkhead box F2a / FOXF2* / O54743* / Q12947* / forkhead box F2* / Forkhead box protein F2 *ENSDARG0000001719519
foxg1c / forkhead box G1cENSDARG0000006838019
foxg1d / forkhead box G1dENSDARG0000007005319
foxh1 / forkhead box H1 / O75593* / O88621* / Forkhead box protein H1 *ENSDARG0000005563018
foxq1a / forkhead box Q1a / FOXQ1* / O70220* / Q9C009* / forkhead box Q1* / Forkhead box protein Q1 *ENSDARG0000003089617
foxq1b / forkhead box Q1b / FOXQ1* / O70220* / Q9C009* / forkhead box Q1* / Forkhead box protein Q1 *ENSDARG0000005539517
si:dkey-7e14.3 / Gm5294* / AC187653.1*ENSDARG0000008605517
foxp2 / forkhead box P2ENSDARG0000000545315
foxq2 / forkhead box Q2ENSDARG0000007139415
foxp1a / forkhead box P1aENSDARG0000000484314


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0002088 lens development in camera-type eye IMP
 biological_processGO:0002089 lens morphogenesis in camera-type eye IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0035904 aorta development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens cell poorly differentiated , abnormal
lens malformed , abnormal
lens pigmented , abnormal
lens actin filament decreased amount , abnormal
lens cell disorganized , abnormal
lens actin filament spatial pattern , abnormal
lens cell shape , abnormal
lens physical object quality , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000640 cornea cornea composition , abnormal
cornea nucleate quality , abnormal
Show

 ZFA:0001283 pupil pupil decreased size , abnormal
pupil absent , abnormal
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 ZFA:0001326 lens epithelium lens epithelium composition , abnormal
lens epithelium has extra parts of type epithelial cell nucleus, abnormal
lens epithelium epithelial cell nucleate quality , abnormal
lens epithelium epithelial cell immature , abnormal
lens epithelium has extra parts of type epithelial cell , abnormal
lens epithelium structure , abnormal
lens epithelium nucleus increased size , abnormal
lens epithelium nucleus disorganized , abnormal
lens epithelium epithelial cell swollen , abnormal
Show

 ZFA:0005004 aortic arch aortic arch morphology , abnormal
aortic arch incomplete structure , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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