ENSMUSG00000044518


Mus musculus

Features
Gene ID: ENSMUSG00000044518
  
Biological name :Foxe3
  
Synonyms : Forkhead box protein E3 / Foxe3 / Q9QY14
  
Possible biological names infered from orthology : forkhead box E3 / Q13461
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D1
Gene start: 114925147
Gene end: 114926013
  
Corresponding Affymetrix probe sets: 10515162 (MoGene1.0st)   1422393_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050445
NCBI entrez gene - 30923     See in Manteia.
MGI - MGI:1353569
RefSeq - NM_015758
RefSeq Peptide - NP_056573
swissprot - Q9QY14
Ensembl - ENSMUSG00000044518
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxe1ENSDARG00000079266Danio rerio
 foxe3ENSDARG00000062892Danio rerio
 FOXE3ENSG00000186790Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Foxe1 / Q8R2I0 / Forkhead box protein E1 / O00358* / forkhead box E1*ENSMUSG0000007099048
Foxd2 / O35392 / Forkhead box protein D2 / O60548* / forkhead box D2*ENSMUSG0000005521038
Foxd1 / Q61345 / Forkhead box protein D1 / Q16676* / forkhead box D1*ENSMUSG0000007830237
Foxd4 / Q60688 / Forkhead box protein D4 / Q9NU39* / Q12950* / Q3SYB3* / Q5VV16* / Q6VB84* / Q8WXT5* / FOXD4L3* / FOXD4L4* / FOXD4L5* / FOXD4L6* / FOXD4L1* / forkhead box D4* / forkhead bo...ENSMUSG0000005149036
Foxd3 / forkhead box D3 / Q9UJU5*ENSMUSG0000006726136
Foxq1 / O70220 / Forkhead box protein Q1 / Q9C009* / forkhead box Q1*ENSMUSG0000003841530
Foxg1 / Q60987 / Forkhead box protein G1 / P55316* / forkhead box G1*ENSMUSG0000002095028
Foxf2 / O54743 / Forkhead box protein F2 / Q12947* / forkhead box F2*ENSMUSG0000003840227
Foxh1 / O88621 / Forkhead box protein H1 / O75593* / forkhead box H1*ENSMUSG0000003383726
Gm5294 / AC187653.1*ENSMUSG0000009450425
Foxf1 / Q61080 / Forkhead box protein F1 / Q12946* / forkhead box F1*ENSMUSG0000004281224
Foxp4 / Q9DBY0 / Forkhead box protein P4 / Q8IVH2* / forkhead box P4*ENSMUSG0000002399120
Foxp2 / P58463 / Forkhead box protein P2 / O15409* / forkhead box P2*ENSMUSG0000002956320
Foxp1 / P58462 / Mus musculus forkhead box P1 (Foxp1), transcript variant 4, mRNA.ENSMUSG0000003006720
Foxp3 / Q99JB6 / Forkhead box protein P3 Forkhead box protein P3, C-terminally processed Forkhead box protein P3 41 kDa form / Q9BZS1* / forkhead box P3*ENSMUSG0000003952116
Gm43517ENSMUSG0000008992214


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IEA
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0002930 trabecular meshwork development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0042789 mRNA transcription by RNA polymerase II IEA
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0048468 cell development IMP
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IMP
 biological_processGO:0061072 iris morphogenesis IMP
 biological_processGO:0061073 ciliary body morphogenesis IMP
 biological_processGO:0061303 cornea development in camera-type eye IMP
 biological_processGO:0071157 negative regulation of cell cycle arrest IEA
 biological_processGO:1902747 negative regulation of lens fiber cell differentiation IMP
 biological_processGO:2001111 positive regulation of lens epithelial cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000272 abnormal aorta morphology "structural anomaly of the main trunk of the systemic arteries" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001288 abnormal lens induction "malformation of or failure to form the transparent, biconvex structure of the eye which is situated behind the iris and in front of the vitreous humor" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001292 abnormal lens vesicle development "malformation or abnormal patterning of the lens vesicle of the eye" [J:49424]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3rct/Foxe3rct,mrct/mrct
Genetic Background: SJL/J

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Foxe3rct/Foxe3rct
Genetic Background: SJL/J-Foxe3rct

 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3rct/Foxe3rct,mrct/mrct
Genetic Background: SJL/J

Allelic Composition: Foxe3rct/Foxe3rct
Genetic Background: SJL/J-Foxe3rct

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3rct/Foxe3rct,mrct/mrct
Genetic Background: SJL/J

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

Allelic Composition: Foxe3dyl/Foxe3tm1Pca
Genetic Background: C.Cg-Foxe3dyl/Foxe3tm1Pca

Allelic Composition: Foxe3rct/Foxe3rct
Genetic Background: SJL/J-Foxe3rct

 MP:0001306 small lens "reduced size of the transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

Allelic Composition: Foxe3dyl/Foxe3tm1Pca
Genetic Background: C.Cg-Foxe3dyl/Foxe3tm1Pca

 MP:0001307 fused cornea/lens "condition in which the transparent anterior portion of the fibrous coat of the eye is joined to the transparent biconvex cellular refractive structure lying between the iris and vitreous humor of the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

Allelic Composition: Foxe3dyl/Foxe3tm1Pca
Genetic Background: C.Cg-Foxe3dyl/Foxe3tm1Pca

 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

 MP:0001314 corneal opacity "complete or partial clouding of the cornea" [jte:Janan T. Eppig , Mouse Genome Informatics, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

 MP:0001320 small pupils "smaller than normal size of the central circular aperture of the iris through which light rays enter the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001322 abnormal iris morphology "structural anomaly of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3dyl/Foxe3+
Genetic Background: BALB/cLiA-Foxe3dyl

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

Allelic Composition: Foxe3tm1Pca/Foxe3+
Genetic Background: C.129-Foxe3tm1Pca

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002579 disorganized secondary lens fibers "deformation or misalignment of the elongated cells that form the crystalline lens" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:70385]
Show

Allelic Composition: Foxe3rct/Foxe3rct
Genetic Background: SJL/J-Foxe3rct

 MP:0002638 abnormal pupillary reflex "alterations or failure of the pupil to change in diamater as a reflex response to any stimulus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Foxe3rct/Foxe3rct
Genetic Background: SJL/J-Foxe3rct

 MP:0003237 abnormal lens epithelium morphology "malformation in the one or more of the layers of epithelial cells in the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Foxe3rct/Foxe3rct
Genetic Background: SJL/J-Foxe3rct

 MP:0004113 abnormal aortic arch morphology "structural anomoly of the portion of the descending aorta proceeding from the arch of the aorta and extending to the diaphragm " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004221 abnormal iridocorneal angle "any structural abnormality of the acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

 MP:0004224 absent trabecular meshwork "absence of the pore-like structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates" [MESH:A09.371.060.932, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

 MP:0004283 absent corneal endothelium "absence of the single layer of large flattened cells that cover the surface of the cornea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004484 altered response of heart to induced stress "change in the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005099 abnormal ciliary body morphology "structural anomaly of the thickened portion of the vascular tunic, which lies between the choroid and the iris" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

 MP:0005176 eyelids fail to open "eyes remain shut throughout life" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005193 abnormal anterior eye segment morphology "anomalous structure of any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxe3dyl/Foxe3+
Genetic Background: BALB/cLiA-Foxe3dyl

Allelic Composition: Foxe3tm1Pca/Foxe3+
Genetic Background: C.129-Foxe3tm1Pca

 MP:0005204 abnormal canal of Schlemm morphology "structural anomaly in the vascular structure encircling the anterior chamber of the eye, through which the aqueous humor is returned to the blood circulation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

 MP:0005205 abnormal eye anterior chamber "anomaly of the space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005300 abnormal corneal stroma morphology "structural anomaly of the lamellated connective tissue of the cornea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Foxe3dyl/Foxe3+
Genetic Background: BALB/cLiA-Foxe3dyl

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

Allelic Composition: Foxe3tm1Pca/Foxe3+
Genetic Background: C.129-Foxe3tm1Pca

 MP:0005301 abnormal corneal endothelium morphology "anomalous structure of the single layer of large flattened cells that cover the surface of the cornea" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3dyl/Foxe3+
Genetic Background: BALB/cLiA-Foxe3dyl

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

Allelic Composition: Foxe3tm1Pca/Foxe3+
Genetic Background: C.129-Foxe3tm1Pca

 MP:0005542 corneal vascularization "formation of blood vessels in the cornea, which normally lacks vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

 MP:0005545 abnormal lens development "aberrant formation of the transparent structure of the eye responsible for focusing light rays" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Foxe3dyl/Foxe3tm1Pca
Genetic Background: C.Cg-Foxe3dyl/Foxe3tm1Pca

Allelic Composition: Foxe3rct/Foxe3rct
Genetic Background: SJL/J-Foxe3rct

 MP:0005595 abnormal vascular smooth muscle physiology "anomalous function of the nonstriated, involuntary muscle tissue of the blood vessels" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0006000 abnormal corneal epithelium "malformation in the one or more of the layers of epithelial cells covering the front of the cornea" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0006226 iris hypoplasia "less than the normal number of cells in the iris" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxe3dyl/Foxe3+
Genetic Background: BALB/cLiA-Foxe3dyl

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

Allelic Composition: Foxe3tm1Pca/Foxe3+
Genetic Background: C.129-Foxe3tm1Pca

 MP:0008817 hematoma "an abnormal localized accumulation of clotted or partially clotted blood in an organ or a soft tissue space as a result of localized hemorrhage" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0009763 increased sensitivity to induced morbidity/mortality "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0009867 abnormal ascending aorta morphology "any structural anomaly of the portion of the aorta that arises from the base of the left ventricle and extends upward to the aortic arch and from which the coronary arteries arise" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010255 cortical cataracts "a lens opacity, frequently punctate, affecting the lens cortex in which spokes or wedges progressively extend from the outside of the lens towards the center" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Foxe3rct/Foxe3rct
Genetic Background: SJL/J-Foxe3rct

 MP:0010259 anterior polar cataracts "a lens opacity, usually disk-shaped, that is limited to an area in the anterior pole of the lens capsular region" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Foxe3rct/Foxe3rct
Genetic Background: SJL/J-Foxe3rct

 MP:0010470 ascending aorta dilation "the luminal space of the ascending aorta is increased in volume or area, usually with an increase of contained fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010713 corneal-lenticular stalk "persistent central adhesion between the lens and the cornea" [PMID:18653562]
Show

Allelic Composition: Tnftm1Ljo/Tnf+
Genetic Background: involves: 129S1/Sv

 MP:0011481 anterior iris synechia "adhesion of the iris to the cornea" [MGI:anna]
Show

Allelic Composition: Foxe3dyl/Foxe3+
Genetic Background: BALB/cLiA-Foxe3dyl

Allelic Composition: Foxe3tm1Pca/Foxe3tm1Pca
Genetic Background: C.129-Foxe3tm1Pca

Allelic Composition: Foxe3tm1Pca/Foxe3+
Genetic Background: C.129-Foxe3tm1Pca

 MP:0011697 vacuolated lens "fluid filled cavities are present in the cytoplasm of the transparent structure of the eye responsible for focusing light" [MGI:llw2]
Show

Allelic Composition: Foxe3tm1Mjam/Foxe3tm1Mjam
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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