ENSDARG00000063218


Danio rerio

Features
Gene ID: ENSDARG00000063218
  
Biological name :ppm1la
  
Synonyms : ppm1la / protein phosphatase, Mg2+/Mn2+ dependent, 1La
  
Possible biological names infered from orthology : PPM1L / Protein phosphatase 1L / protein phosphatase, Mg2+/Mn2+ dependent 1L / Q5SGD2 / Q8BHN0
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 6265768
Gene end: 6292510
  
Corresponding Affymetrix probe sets: Dr.7261.1.A1_at (Zebrafish Array)   NM_001077600_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000086614
NCBI entrez gene - 556994     See in Manteia.
RefSeq - NM_001077600
RefSeq Peptide - NP_001071068
swissprot - A0JMP2
ZFIN ID - ZDB-GENE-061103-118
Ensembl - ENSDARG00000063218
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PPM1LENSGALG00000009537Gallus gallus
 PPM1LENSG00000163590Homo sapiens
 Ppm1lENSMUSG00000027784Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppm1lb / protein phosphatase, Mg2+/Mn2+ dependent, 1Lb / PPM1L* / Q8BHN0* / Q5SGD2* / Protein phosphatase 1L * / protein phosphatase, Mg2+/Mn2+ dependent 1L*ENSDARG0000008964165
ppm1k / protein phosphatase, Mg2+/Mn2+ dependent, 1K / Q8BXN7* / Q8N3J5* / protein phosphatase 1K (PP2C domain containing)*ENSDARG0000001065529
si:ch211-149b19.3 / PPM1K* / Q8N3J5* / Q8BXN7* / protein phosphatase, Mg2+/Mn2+ dependent 1K* / protein phosphatase 1K (PP2C domain containing)*ENSDARG0000007601129
ppm1e / protein phosphatase, Mg2+/Mn2+ dependent, 1E / Q80TL0* / Q8WY54* / Protein phosphatase 1E *ENSDARG0000002649928
ppm1f / protein phosphatase, Mg2+/Mn2+ dependent, 1F / P49593* / Q8CGA0* / Protein phosphatase 1F *ENSDARG0000000578625
ilkap / integrin-linked kinase-associated serine/threonine phosphatase / Q8R0F6* / Q9H0C8* / ILK associated serine/threonine phosphatase* / Mus musculus integrin-linked kinase-associated se...ENSDARG0000004061525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000222  PPM-type phosphatase, divalent cation binding
 IPR001932  PPM-type phosphatase domain
 IPR015655  Protein phosphatase 2C family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000070435 vapb / VAMP (vesicle-associated membrane protein)-associated protein B and C / O95292* / VAMP associated protein B and C* / vesicle-associated membrane protein, associated protein B and C*  / complex
 ENSDARG00000024325 col4a3bpa / collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a / Q9EQG9* / Q9Y5P4* / COL4A3BP* / collagen type IV alpha 3 binding protein*  / complex / reaction






 

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