ENSDARG00000063253


Danio rerio

Features
Gene ID: ENSDARG00000063253
  
Biological name :hecw2b
  
Synonyms : HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2b / hecw2b
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase HECW2 / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 / HECW2 / Q6I6G8 / Q9P2P5
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 6357059
Gene end: 6366066
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000140374
swissprot - A0A0R4ITM9
ZFIN ID - ZDB-GENE-101001-3
Ensembl - ENSDARG00000063253
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HECW2ENSGALG00000007944Gallus gallus
 HECW2ENSG00000138411Homo sapiens
 Hecw2ENSMUSG00000042807Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hecw2a / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a / HECW2* / Q9P2P5* / Q6I6G8* / E3 ubiquitin-protein ligase HECW2 * / HECT, C2 and WW domain containing E3 ubiquitin...ENSDARG0000006244795
hecw1b / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1b / HECW1* / Q8K4P8* / Q76N89* / E3 ubiquitin-protein ligase HECW1 * / HECT, C2 and WW domain containing E3 ubiquitin...ENSDARG0000000429188
si:ch211-188f17.1 / HECW1* / Q76N89* / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1*ENSDARG0000010095887
itcha / itchy E3 ubiquitin protein ligase a / ITCH* / Q8C863* / Q96J02* / itchy E3 ubiquitin protein ligase* / E3 ubiquitin-protein ligase Itchy *ENSDARG0000007490352
wwp1 / WW domain containing E3 ubiquitin protein ligase 1 / Q8BZZ3* / Q9H0M0*ENSDARG0000009753752
smurf1 / SMAD specific E3 ubiquitin protein ligase 1 / Q9CUN6* / Q9HCE7* / E3 ubiquitin-protein ligase SMURF1 *ENSDARG0000001608651
wwp2 / WW domain containing E3 ubiquitin protein ligase 2 / O00308* / Q9DBH0*ENSDARG0000006134549
A9JRZ0 / smurf2 / SMAD specific E3 ubiquitin protein ligase 2 / A2A5Z6* / Q9HAU4* / E3 ubiquitin-protein ligase SMURF2 *ENSDARG0000003806747
nedd4l / neural precursor cell expressed, developmentally down-regulated 4-like / Q96PU5* / neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase*ENSDARG0000006000647
itchb / itchy E3 ubiquitin protein ligase b / ITCH* / Q96J02* / itchy E3 ubiquitin protein ligase*ENSDARG0000009919943
hace1 / HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 / Q8IYU2*ENSDARG0000006228041
nedd4a / neural precursor cell expressed, developmentally down-regulated 4a / NEDD4* / P46934* / P46935* / neural precursor cell expressed, developmentally down-regulated 4* / neural precur...ENSDARG0000009984321
LO018629.1 / HECW2* / Q6I6G8* / Q9P2P5* / E3 ubiquitin-protein ligase HECW2 * / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2*ENSDARG000001138480


Protein motifs (from Interpro)
Interpro ID Name
 IPR000569  HECT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr