ENSDARG00000067607


Danio rerio

Features
Gene ID: ENSDARG00000067607
  
Biological name :srebf1
  
Synonyms : srebf1 / sterol regulatory element binding transcription factor 1
  
Possible biological names infered from orthology : Mus musculus sterol regulatory element binding transcription factor 1 (Srebf1), transcript variant 4, mRNA. / P36956 / Q9WTN3
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 62064805
Gene end: 62087346
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000087097
swissprot - F1RDU4
ZFIN ID - ZDB-GENE-090812-3
Ensembl - ENSDARG00000067607
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SREBF1ENSGALG00000027188Gallus gallus
 P36956ENSG00000072310Homo sapiens
 Q9WTN3ENSMUSG00000020538Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
srebf2 / sterol regulatory element binding transcription factor 2 / Q12772* / Q3U1N2* / sterol regulatory element binding factor 2*ENSDARG0000006343836


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IGI
 biological_processGO:0003323 type B pancreatic cell development IMP
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:1990798 pancreas regeneration IMP
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Regulation of cholesterol biosynthesis by SREBP (SREBF)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased size , abnormal
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 ZFA:0009102 pancreatic B cell pancreatic B cell increased amount , abnormal
pancreatic B cell decreased distribution , abnormal
pancreatic B cell decreased amount , abnormal
pancreatic B cell decreased area , abnormal
pancreatic B cell regeneration decreased rate , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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