ENSDARG00000069763


Danio rerio

Features
Gene ID: ENSDARG00000069763
  
Biological name :etv5a
  
Synonyms : ets variant 5a / etv5a
  
Possible biological names infered from orthology : ETS translocation variant 1 / ETS variant 1 / ETV1 / P41164 / P50549
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 22631672
Gene end: 22649297
  
Corresponding Affymetrix probe sets: Dr.11545.1.S1_at (Zebrafish Array)   Dr.23024.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000108566
Ensembl peptide - ENSDARP00000156093
Ensembl peptide - ENSDARP00000123061
Ensembl peptide - ENSDARP00000114176
Ensembl peptide - ENSDARP00000092546
NCBI entrez gene - 337626     See in Manteia.
RefSeq - NM_001126461
RefSeq - XM_021478612
RefSeq - XM_021478613
RefSeq Peptide - NP_001119933
swissprot - B0S6S7
swissprot - B0S6S6
swissprot - B0S6S5
swissprot - F1Q6X6
ZFIN ID - ZDB-GENE-030131-9572
Ensembl - ENSDARG00000069763
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ETV1ENSGALG00000035504Gallus gallus
 ETV1ENSG00000006468Homo sapiens
 Etv1ENSMUSG00000004151Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
etv5b / ets variant 5bENSDARG0000004451166
etv1 / ets variant 1ENSDARG0000010195954
etv4 / ets variant 4 / P28322* / P43268* / ETS translocation variant 4 *ENSDARG0000001830346
fli1a / Fli-1 proto-oncogene, ETS transcription factor a / FLI1* / P26323* / Q01543* / Fli-1 proto-oncogene, ETS transcription factor* / Friend leukemia integration 1 transcription factor *ENSDARG0000005463217
ets2 / v-ets avian erythroblastosis virus E26 oncogene homolog 2 / ETS1* / P14921* / P27577* / Protein C-ets-1 * / ETS proto-oncogene 1, transcription factor*ENSDARG0000010398016
fli1b / Fli-1 proto-oncogene, ETS transcription factor bENSDARG0000004008015
gabpa / GA binding protein transcription factor, alpha subunit / Q00422* / Q06546* / GA-binding protein alpha chain *ENSDARG0000006928915
erg / v-ets avian erythroblastosis virus E26 oncogene homolog / FLI1* / Q01543* / Fli-1 proto-oncogene, ETS transcription factor*ENSDARG0000007730415
etv2 / ets variant 2 / O00321* / P41163* / ETS translocation variant 2 *ENSDARG0000005386814
fev / A3FEM2 / FEV (ETS oncogene family)ENSDARG0000000924212
elk4 / ELK4, ETS-domain protein / P28324* / P41158* / ELK4, ETS transcription factor* / ETS domain-containing protein Elk-4 *ENSDARG0000007709212
elk3 / ELK3, ETS-domain protein / P41970* / P41971* / ELK3, ETS transcription factor* / ETS domain-containing protein Elk-3 *ENSDARG0000001868811
erfl3 / Ets2 repressor factor like 3ENSDARG0000006280111
elk1 / ELK1, member of ETS oncogene family / P19419* / P41969* / ELK1, ETS transcription factor* / ETS domain-containing protein Elk-1 *ENSDARG0000007806611
erfl1 / Ets2 repressor factor like 1 / ERF* / Gm4881* / P50548* / AC010616.1* / ETS2 repressor factor*ENSDARG0000008689211
erf / Ets2 repressor factorENSDARG0000006341710
si:ch211-265g22.4ENSDARG000000765128
CABZ01069595.1 / ELK4* / P28324* / ELK4, ETS transcription factor*ENSDARG000000244315


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR006715  PEA3-type ETS-domain transcription factor, N-terminal
 IPR011991  ArsR-like helix-turn-helix domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0035108 limb morphogenesis IGI
 biological_processGO:0035778 pronephric nephron tubule epithelial cell differentiation IMP
 biological_processGO:0060217 hemangioblast cell differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000083 ventral mesoderm ventral mesoderm cell proliferation increased occurrence , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0000151 pronephros pronephros spatial pattern , ameliorated
pronephros absent , abnormal
pronephros increased distribution , abnormal
pronephros decreased distribution , abnormal
pronephros has fewer parts of type pronephros multi-ciliated epithelial cell, abnormal
pronephros has extra parts of type pronephros multi-ciliated epithelial cell, abnormal
pronephros multi-ciliated epithelial cell differentiation occurrence , ameliorated
pronephros multi-ciliated epithelial cell differentiation arrested , abnormal
pronephros multi-ciliated epithelial cell differentiation increased occurrence , abnormal
pronephros multi-ciliated epithelial cell differentiation decreased occurrence , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head hemorrhagic , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
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 ZFA:0001621 pronephric proximal straight tubule pronephric proximal straight tubule has number of pronephric proximal straight tubule multi-ciliated epithelial cell, ameliorated
pronephric proximal straight tubule lacks all parts of type pronephric proximal straight tubule multi-ciliated epithelial cell, abnormal
pronephric proximal straight tubule has fewer parts of type pronephric proximal straight tubule multi-ciliated epithelial cell, abnormal
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 ZFA:0005035 subintestinal vein subintestinal vein hypoplastic , abnormal
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 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased amount , abnormal
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 ZFA:0009023 common lymphoid progenitor common lymphoid progenitor decreased amount , abnormal
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 ZFA:0009044 blood cell blood cell decreased amount , abnormal
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 ZFA:0009048 granulocyte granulocyte decreased amount , abnormal
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 ZFA:0009325 erythroid lineage cell erythroid lineage cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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