ENSDARG00000070426


Danio rerio

Features
Gene ID: ENSDARG00000070426
  
Biological name :chac1
  
Synonyms : chac1 / ChaC, cation transport regulator homolog 1 (E. coli) / Q5SPB6
  
Possible biological names infered from orthology : ChaC glutathione specific gamma-glutamylcyclotransferase 1 / Glutathione-specific gamma-glutamylcyclotransferase 1 / Q8R3J5 / Q9BUX1
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 28266892
Gene end: 28269462
  
Corresponding Affymetrix probe sets: Dr.24239.1.S1_at (Zebrafish Array)   Dr.24811.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000094107
NCBI entrez gene - 563855     See in Manteia.
RefSeq - NM_001110126
RefSeq Peptide - NP_001103596
swissprot - A4QNY6
swissprot - Q5SPB6
ZFIN ID - ZDB-GENE-030131-1957
Ensembl - ENSDARG00000070426
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CHAC1ENSGALG00000027874Gallus gallus
 CHAC1ENSG00000128965Homo sapiens
 Chac1ENSMUSG00000027313Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
chac2 / Q4KMJ1 / ChaC, cation transport regulator homolog 2 (E. coli) / Q9CQG1* / Q8WUX2* / ChaC cation transport regulator homolog 2* / Putative glutathione-specific gamma-glutamylcyclotra...ENSDARG0000005507843


Protein motifs (from Interpro)
Interpro ID Name
 IPR006840  Glutathione-specific gamma-glutamylcyclotransferase
 IPR013024  Gamma-glutamyl cyclotransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006751 glutathione catabolic process IBA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010955 negative regulation of protein processing ISS
 biological_processGO:0022008 neurogenesis ISS
 biological_processGO:0045746 negative regulation of Notch signaling pathway ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network ISS
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003839 gamma-glutamylcyclotransferase activity IBA
 molecular_functionGO:0005112 Notch binding ISS
 molecular_functionGO:0016829 lyase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione synthesis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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