ENSMUSG00000027313


Mus musculus

Features
Gene ID: ENSMUSG00000027313
  
Biological name :Chac1
  
Synonyms : Chac1 / Glutathione-specific gamma-glutamylcyclotransferase 1 / Q8R3J5
  
Possible biological names infered from orthology : ChaC glutathione specific gamma-glutamylcyclotransferase 1 / Q9BUX1
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: E5
Gene start: 119351229
Gene end: 119354381
  
Corresponding Affymetrix probe sets: 10474972 (MoGene1.0st)   1451382_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028780
NCBI entrez gene - 69065     See in Manteia.
MGI - MGI:1916315
RefSeq - NM_026929
RefSeq Peptide - NP_081205
swissprot - Q8R3J5
Ensembl - ENSMUSG00000027313
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chac1ENSDARG00000070426Danio rerio
 CHAC1ENSGALG00000027874Gallus gallus
 CHAC1ENSG00000128965Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chac2 / Q9CQG1 / Putative glutathione-specific gamma-glutamylcyclotransferase 2 / Q8WUX2* / ChaC cation transport regulator homolog 2*ENSMUSG0000002030940


Protein motifs (from Interpro)
Interpro ID Name
 IPR006840  Glutathione-specific gamma-glutamylcyclotransferase
 IPR013024  Gamma-glutamyl cyclotransferase-like
 IPR036568  Gamma-glutamyl cyclotransferase-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006751 glutathione catabolic process IBA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010955 negative regulation of protein processing IEA
 biological_processGO:0022008 neurogenesis IMP
 biological_processGO:0045746 negative regulation of Notch signaling pathway IEA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0003839 gamma-glutamylcyclotransferase activity IBA
 molecular_functionGO:0005112 Notch binding IDA
 molecular_functionGO:0016829 lyase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione synthesis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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