ENSDARG00000071048


Danio rerio

Features
Gene ID: ENSDARG00000071048
  
Biological name :wisp3
  
Synonyms : wisp3 / WNT1 inducible signaling pathway protein 3
  
Possible biological names infered from orthology : D3Z5L9 / O95389
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 276753
Gene end: 284865
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000095576
NCBI entrez gene - 794092     See in Manteia.
swissprot - D0E2W2
ZFIN ID - ZDB-GENE-041001-86
Ensembl - ENSDARG00000071048
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000019934Gallus gallus
 WISP3ENSG00000112761Homo sapiens
 Wisp3ENSMUSG00000062074Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wisp1b / WNT1 inducible signaling pathway protein 1b / WISP1* / O95388* / O54775* / WNT1 inducible signaling pathway protein 1*ENSDARG0000007668542
wisp1a / WNT1 inducible signaling pathway protein 1a / WISP1* / O95388* / O54775* / WNT1 inducible signaling pathway protein 1*ENSDARG0000005433141
ctgfa / connective tissue growth factor a / CTGF* / P29268* / P29279* / connective tissue growth factor*ENSDARG0000004293436
ctgfb / connective tissue growth factor bENSDARG0000010429236
wisp2 / WNT1 inducible signaling pathway protein 2 / O76076*ENSDARG0000007788232
cyr61 / cysteine-rich, angiogenic inducer, 61 / O00622*ENSDARG0000002306231
si:ch211-106h11.3ENSDARG0000002736031
cyr61l1 / cysteine-rich, angiogenic inducer 61 like 1ENSDARG0000003542230
cyr61l2 / cysteine-rich, angiogenic inducer, 61 like 2ENSDARG0000009998530


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR006207  Cystine knot, C-terminal
 IPR006208  Glycoprotein hormone subunit beta
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR017891  Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IGI
 biological_processGO:0030509 BMP signaling pathway IGI
 biological_processGO:0030514 negative regulation of BMP signaling pathway IGI
 biological_processGO:0051216 cartilage development IMP
 biological_processGO:0060548 negative regulation of cell death IBA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005178 integrin binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0008201 heparin binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001273 ventral mandibular arch ventral mandibular arch decreased length , abnormal
ventral mandibular arch decreased size , abnormal
ventral mandibular arch chondrocyte decreased amount , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage shape , abnormal
Show

 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage shape , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage fragile , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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