ENSDARG00000071699


Danio rerio

Features
Gene ID: ENSDARG00000071699
  
Biological name :ids
  
Synonyms : ids / iduronate 2-sulfatase
  
Possible biological names infered from orthology : AC244197.3 / P22304 / Q08890
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 20869618
Gene end: 20891769
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000096983
NCBI entrez gene - 559959     See in Manteia.
RefSeq - NM_001080068
RefSeq Peptide - NP_001073537
swissprot - F1R4Q5
ZFIN ID - ZDB-GENE-061215-37
Ensembl - ENSDARG00000071699
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IDSENSGALG00000009154Gallus gallus
 AC244197.3ENSG00000241489Homo sapiens
 IDSENSG00000010404Homo sapiens
 IdsENSMUSG00000035847Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arsk / arylsulfatase family, member K / Q6UWY0*ENSDARG0000005971419


Protein motifs (from Interpro)
Interpro ID Name
 IPR000917  Sulfatase, N-terminal
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR024607  Sulfatase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007224 smoothened signaling pathway IMP
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0060347 heart trabecula formation IMP
 biological_processGO:0060536 cartilage morphogenesis IMP
 biological_processGO:0061316 canonical Wnt signaling pathway involved in heart development IMP
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004423 iduronate-2-sulfatase activity IDA
 molecular_functionGO:0008484 sulfuric ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
HS-GAG degradation
CS/DS degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle heart trabecula formation disrupted , abnormal
cardiac ventricle heart trabecula formation disrupted , ameliorated
Show

 ZFA:0000084 yolk yolk vasculature decreased amount , abnormal
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 ZFA:0000115 heart rudiment heart rudiment smoothened signaling pathway disrupted , abnormal
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 ZFA:0000173 bulbus arteriosus bulbus arteriosus increased amount , abnormal
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 ZFA:0000360 heart tube heart tube decreased amount , abnormal
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 ZFA:0000471 atrium atrium increased size , abnormal
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 ZFA:0001094 whole organism whole organism decreased amount , abnormal
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 ZFA:0001114 head head deformed , abnormal
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 ZFA:0001115 trunk trunk decreased size , abnormal
trunk neural tube decreased amount , abnormal
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 ZFA:0001117 post-vent region post-vent region neural tube decreased amount , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage deformed , abnormal
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 ZFA:0001315 atrioventricular canal atrioventricular canal increased amount , abnormal
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 ZFA:0001319 myocardium myocardium increased thickness , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage deformed , abnormal
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 ZFA:0001510 basihyal cartilage basihyal cartilage deformed , abnormal
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 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 deformed , abnormal
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 ZFA:0005060 trabecular layer of ventricle trabecular layer of ventricle decreased size , abnormal
trabecular layer of ventricle decreased size , ameliorated
Show

 ZFA:0005064 atrioventricular valve atrioventricular valve disorganized , abnormal
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 ZFA:0005810 trabecular layer of the atrium trabecular layer of the atrium absent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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