ENSDARG00000075354


Danio rerio

Features
Gene ID: ENSDARG00000075354
  
Biological name :espl1
  
Synonyms : espl1 / extra spindle pole bodies like 1, separase
  
Possible biological names infered from orthology : Mus musculus extra spindle pole bodies 1, separase (Espl1), transcript variant 2, mRNA. / P60330 / Q14674
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 39668850
Gene end: 39700965
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000128879
NCBI entrez gene - 797406     See in Manteia.
RefSeq - XM_005166094
RefSeq - XM_021471828
RefSeq - XM_021471829
RefSeq - XM_001337833
RefSeq - XM_021477220
RefSeq - XM_021477221
RefSeq - XM_021474123
RefSeq - XM_021474124
swissprot - E7FDD8
ZFIN ID - ZDB-GENE-030131-5188
Ensembl - ENSDARG00000075354
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ESPL1ENSG00000135476Homo sapiens
 Espl1ENSMUSG00000058290Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005314  Peptidase C50, separase
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR030397  SEPARIN core domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0051307 meiotic chromosome separation IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005813 centrosome IBA
 cellular_componentGO:0072686 mitotic spindle IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA


Pathways (from Reactome)
Pathway description
Separation of Sister Chromatids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001094 whole organism whole organism ploidy , abnormal
whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head apoptotic , abnormal
Show

 ZFA:0001117 post-vent region post-vent region apoptotic , abnormal
post-vent region curvature , abnormal
Show

 ZFA:0001338 intestine intestine hypertrophic , abnormal
intestine adenoma present , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000075354 espl1 / extra spindle pole bodies like 1, separase / P60330* / Q14674* / Mus musculus extra spindle pole bodies 1, separase (Espl1), transcript variant 2, mRNA.*  / complex






 

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