ENSDARG00000075454


Danio rerio

Features
Gene ID: ENSDARG00000075454
  
Biological name :hdc
  
Synonyms : hdc / histidine decarboxylase
  
Possible biological names infered from orthology : P19113 / P23738
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 73434
Gene end: 81280
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124833
Ensembl peptide - ENSDARP00000124929
swissprot - F8W271
swissprot - F8W5Y8
ZFIN ID - ZDB-GENE-080102-5
Ensembl - ENSDARG00000075454
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HDCENSGALG00000023436Gallus gallus
 HDCENSG00000140287Homo sapiens
 HdcENSMUSG00000027360Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ddc / dopa decarboxylase / O88533* / P20711* / Aromatic-L-amino-acid decarboxylase *ENSDARG0000001649449
zgc:163121ENSDARG0000005537023
gad1b / glutamate decarboxylase 1b / GAD1* / Q99259* / P48318* / glutamate decarboxylase 1*ENSDARG0000002741922
gad1a / glutamate decarboxylase 1a / GAD1* / Q99259* / P48318* / glutamate decarboxylase 1*ENSDARG0000009341122
gad2 / glutamate decarboxylase 2 / P48320* / Q05329* / glutamic acid decarboxylase 2*ENSDARG0000001553721
csad / cysteine sulfinic acid decarboxylase / Q9DBE0* / Q9Y600*ENSDARG0000002634820


Protein motifs (from Interpro)
Interpro ID Name
 IPR002129  Pyridoxal phosphate-dependent decarboxylase
 IPR010977  Aromatic-L-amino-acid decarboxylase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR021115  Pyridoxal-phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006520 cellular amino acid metabolic process IEA
 biological_processGO:0007268 chemical synaptic transmission IMP
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0009416 response to light stimulus IMP
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Histidine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
brain histamine decreased amount , abnormal
Show

 ZFA:0000032 hypothalamus hypothalamus neuron absent , abnormal
hypothalamus neuron decreased distribution , abnormal
hypothalamus neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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