ENSDARG00000076140


Danio rerio

Features
Gene ID: ENSDARG00000076140
  
Biological name :clcf1
  
Synonyms : cardiotrophin-like cytokine factor 1 / clcf1
  
Possible biological names infered from orthology : Cardiotrophin-2 / Ctf2 / P83714 / Q9QZM3 / Q9UBD9
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 22022441
Gene end: 22038396
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124677
NCBI entrez gene - 562247     See in Manteia.
RefSeq - XM_021481150
RefSeq - XM_685641
swissprot - F8W2M3
ZFIN ID - ZDB-GENE-110411-244
Ensembl - ENSDARG00000076140
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CLCF1ENSG00000175505Homo sapiens
 Clcf1ENSMUSG00000040663Mus musculus
 Ctf2ENSMUSG00000060034Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009079  Four-helical cytokine-like, core
 IPR010681  Plethodontid receptivity factor PRF/cardiotrophin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0048680 positive regulation of axon regeneration IMP
 cellular_componentGO:0005576 extracellular region IBA
 molecular_functionGO:0005125 cytokine activity IBA


Pathways (from Reactome)
Pathway description
IL-6-type cytokine receptor ligand interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009310 retinal ganglion cell retinal ganglion cell axon regeneration decreased process quality , abnormal
retinal ganglion cell axon extension involved in regeneration decreased process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006368 crlf1b / cytokine receptor-like factor 1b / CRLF1* / O75462* / Q9JM58* / cytokine receptor like factor 1*  / complex / reaction
 ENSDARG00000018882 jak2b / Janus kinase 2b / JAK2* / O60674* / Janus kinase 2*  / complex / reaction
 ENSDARG00000020625 jak1 / Janus kinase 1 / P23458*  / complex / reaction
 ENSDARG00000024365 crlf1a / cytokine receptor-like factor 1a / CRLF1* / O75462* / Q9JM58* / cytokine receptor like factor 1*  / complex / reaction
 ENSDARG00000028661 cntfr / ciliary neurotrophic factor receptor / O88507* / P26992* / Ciliary neurotrophic factor receptor subunit alpha *  / complex / reaction
 ENSDARG00000104693 il6st / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *  / complex / reaction
 ENSDARG00000104808 jak2a / Janus kinase 2a / JAK2* / O60674* / Janus kinase 2*  / complex / reaction






 

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