ENSDARG00000076262


Danio rerio

Features
Gene ID: ENSDARG00000076262
  
Biological name :pou3f2b
  
Synonyms : P79746 / pou3f2b / POU class 3 homeobox 2b
  
Possible biological names infered from orthology : P20265 / P31360 / POU3F2 / POU class 3 homeobox 2 / POU domain, class 3, transcription factor 2
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 32559821
Gene end: 32563092
  
Corresponding Affymetrix probe sets: Dr.221.1.S1_at (Zebrafish Array)   NM_131160_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000087682
NCBI entrez gene - 30397     See in Manteia.
RefSeq - NM_131160
RefSeq Peptide - NP_571235
swissprot - P79746
ZFIN ID - ZDB-GENE-980526-370
Ensembl - ENSDARG00000076262
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POU3F2ENSGALG00000038425Gallus gallus
 P20265ENSG00000184486Homo sapiens
 P31360ENSMUSG00000095139Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pou3f2a / POU class 3 homeobox 2aENSDARG0000007022071
P56224 / pou3f3a / POU class 3 homeobox 3aENSDARG0000004203265
P79745 / pou3f3b / POU class 3 homeobox 3bENSDARG0000009589664
Q90482 / pou3f1 / POU class 3 homeobox 1 / Q03052* / P21952* / POU domain, class 3, transcription factor 1 *ENSDARG0000000982356
pou2f1b / POU class 2 homeobox 1b / P25425* / POU2F1* / P14859* / POU class 2 homeobox 1* / POU domain, class 2, transcription factor 1 *ENSDARG0000000799634
pou2f2a / POU class 2 homeobox 2a / Q00196* / P09086* / POU2F2* / POU class 2 homeobox 2* / POU domain, class 2, transcription factor 2 *ENSDARG0000001965834
pou5f3 / POU domain, class 5, transcription factor 3 / POU5F2* / Q8N7G0* / P20263* / POU5F1* / Q01860* / Q06416* / POU5F1B* / POU class 5 homeobox 1* / POU class 5 homeobox 1B* / POU domain...ENSDARG0000004477433
pou2f2a / POU class 2 homeobox 2a / Q00196* / P09086* / POU2F2* / POU class 2 homeobox 2* / POU domain, class 2, transcription factor 2 *ENSDARG0000003681632
pou2f3 / POU class 2 homeobox 3 / Q9UKI9*ENSDARG0000005238732
pou4f3 / Q90435 / POU class 4 homeobox 3 / Q15319*ENSDARG0000000620626
zgc:158291ENSDARG0000004437526
pou1f1 / POU class 1 homeobox 1 / P28069* / Q00286* / POU domain, class 1, transcription factor 1*ENSDARG0000005892426
pou4f2 / POU class 4 homeobox 2 / Q12837* / Q63934* / POU domain, class 4, transcription factor 2 *ENSDARG0000006973726
pou4f1 / POU class 4 homeobox 1 / Q01851*ENSDARG0000000555925


Protein motifs (from Interpro)
Interpro ID Name
 IPR000327  POU-specific domain
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR013847  POU domain
 IPR016362  POU-domain transcription factor, class 3
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001885 endothelial cell development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007420 brain development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000470 preoptic area preoptic area absent , abnormal
preoptic area decreased amount , abnormal
Show

 ZFA:0001058 caudal fin caudal fin curled , abnormal
Show

 ZFA:0001094 whole organism whole organism curved , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel decreased amount , abnormal
Show

 ZFA:0005024 trunk vasculature trunk vasculature morphology , abnormal
trunk vasculature decreased amount , abnormal
Show

 ZFA:0009065 endothelial cell endothelial cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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