ENSDARG00000076796


Danio rerio

Features
Gene ID: ENSDARG00000076796
  
Biological name :dlg3
  
Synonyms : discs, large homolog 3 (Drosophila) / dlg3
  
Possible biological names infered from orthology : discs large MAGUK scaffold protein 3 / Disks large homolog 3 / P70175 / Q92796
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 33070284
Gene end: 33177997
  
Corresponding Affymetrix probe sets: Dr.14040.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000073316
Ensembl peptide - ENSDARP00000157371
Ensembl peptide - ENSDARP00000139365
Ensembl peptide - ENSDARP00000137954
Ensembl peptide - ENSDARP00000134731
Ensembl peptide - ENSDARP00000069206
NCBI entrez gene - 564081     See in Manteia.
RefSeq - XM_009291194
RefSeq - XM_021481213
swissprot - A0A0R4INR9
swissprot - A0A0R4IIR7
swissprot - F1QS98
swissprot - A5PKT0
swissprot - A0A0R4IVZ6
ZFIN ID - ZDB-GENE-050208-93
Ensembl - ENSDARG00000076796
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DLG3ENSGALG00000041900Gallus gallus
 DLG3ENSG00000082458Homo sapiens
 Dlg3ENSMUSG00000000881Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dlg2 / discs, large homolog 2 (Drosophila) / Q15700* / Q91XM9* / Disks large homolog 2 * / discs large MAGUK scaffold protein 2*ENSDARG0000009932363
dlg1 / Q5PYH6 / discs, large homolog 1 (Drosophila) / Q12959* / Q811D0* / Disks large homolog 1 * / discs large MAGUK scaffold protein 1*ENSDARG0000000967762
dlg1l / Q5PYH5 / discs, large (Drosophila) homolog 1, like / DLG1* / Q12959* / Q811D0* / Disks large homolog 1 * / discs large MAGUK scaffold protein 1*ENSDARG0000010221659
dlg4a / discs, large homolog 4a (Drosophila) / DLG4* / P78352* / discs large MAGUK scaffold protein 4*ENSDARG0000004192650
dlg4b / discs, large homolog 4b (Drosophila)ENSDARG0000003938534
dlg5a / discs, large homolog 5a (Drosophila) / DLG5* / E9Q9R9* / Q8TDM6* / Disks large homolog 5 * / discs large MAGUK scaffold protein 5*ENSDARG0000007405922
dlg5b.1 / discs, large homolog 5b (Drosophila), tandem duplicate 1 / DLG5* / E9Q9R9* / Q8TDM6* / Disks large homolog 5 * / discs large MAGUK scaffold protein 5*ENSDARG0000009094921
mpp5a / membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5) / MPP5* / Q8N3R9* / Q9JLB2* / membrane palmitoylated protein 5* / membrane protein, palmitoylated 5 (MAGUK p55 subf...ENSDARG0000000627218
tjp2b / tight junction protein 2b (zona occludens 2) / TJP2* / Q9UDY2* / Q9Z0U1* / AL358113.1* / tight junction protein 2* / Tight junction protein ZO-2 *ENSDARG0000002344318
mpp3b / membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3) / MPP3* / Q13368* / membrane palmitoylated protein 3*ENSDARG0000006266718
tjp2a / tight junction protein 2a (zona occludens 2) / TJP2* / Q9UDY2* / Q9Z0U1* / AL358113.1* / tight junction protein 2* / Tight junction protein ZO-2 *ENSDARG0000006330918
tjp1a / tight junction protein 1a / TJP1* / P39447* / Q07157* / tight junction protein 1*ENSDARG0000007750618
mpp3a / membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3) / MPP3* / Q13368* / membrane palmitoylated protein 3*ENSDARG0000001518417
tjp1b / tight junction protein 1b / TJP1* / P39447* / Q07157* / tight junction protein 1*ENSDARG0000007937417
mpp7a / Q6P0D7 / membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7) / MPP7* / Q5T2T1* / membrane palmitoylated protein 7* / MAGUK p55 subfamily member 7 isoform 2 *ENSDARG0000010247017
mpp5b / membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5) / MPP5* / Q8N3R9* / Q9JLB2* / membrane palmitoylated protein 5* / membrane protein, palmitoylated 5 (MAGUK p55 subf...ENSDARG0000000472116
mpp2b / membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2) / MPP2* / Q14168* / Q9WV34* / membrane palmitoylated protein 2* / Mus musculus membrane protein, palmitoylated 2 (M...ENSDARG0000001095716
mpp6b / membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6) / MPP6* / Q9JLB0* / Q9NZW5* / membrane palmitoylated protein 6* / membrane protein, palmitoylated 6 (MAGUK p55 subf...ENSDARG0000002976116
mpp2a / membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2) / MPP2* / Q14168* / Q9WV34* / membrane palmitoylated protein 2* / Mus musculus membrane protein, palmitoylated 2 (M...ENSDARG0000005345316
mpp6a / membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6) / MPP6* / Q9JLB0* / Q9NZW5* / membrane palmitoylated protein 6* / membrane protein, palmitoylated 6 (MAGUK p55 subf...ENSDARG0000005689216


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR016313  Disks large 1-like
 IPR019583  PDZ-associated domain of NMDA receptors
 IPR019590  Disks large homologue 1, N-terminal PEST domain
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0043113 receptor clustering IBA
 biological_processGO:0045197 establishment or maintenance of epithelial cell apical/basal polarity IBA
 biological_processGO:0046037 GMP metabolic process IEA
 biological_processGO:0046710 GDP metabolic process IEA
 biological_processGO:0097120 receptor localization to synapse IBA
 cellular_componentGO:0008328 ionotropic glutamate receptor complex IBA
 cellular_componentGO:0014069 postsynaptic density IBA
 cellular_componentGO:0016323 basolateral plasma membrane IBA
 cellular_componentGO:0045211 postsynaptic membrane IBA
 molecular_functionGO:0004385 guanylate kinase activity IBA
 molecular_functionGO:0035255 ionotropic glutamate receptor binding IBA


Pathways (from Reactome)
Pathway description
Activation of Ca-permeable Kainate Receptor
Neurexins and neuroligins
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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