ENSDARG00000077540


Danio rerio

Features
Gene ID: ENSDARG00000077540
  
Biological name :f2rl1.2
  
Synonyms : coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2 / f2rl1.2
  
Possible biological names infered from orthology : F2RL1 / F2R like trypsin receptor 1 / P55085 / P55086 / Proteinase-activated receptor 2
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 7921717
Gene end: 7928101
  
Corresponding Affymetrix probe sets: Dr.17772.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000125648
Ensembl peptide - ENSDARP00000104375
NCBI entrez gene - 100073342     See in Manteia.
RefSeq - XM_005161489
RefSeq - NM_001098778
RefSeq Peptide - NP_001092248
swissprot - I3IRY7
swissprot - F1R280
ZFIN ID - ZDB-GENE-070615-24
Ensembl - ENSDARG00000077540
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F2RL1ENSGALG00000014984Gallus gallus
 F2RL1ENSG00000164251Homo sapiens
 F2rl1ENSMUSG00000021678Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
f2rl1.1 / coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1 / F2RL1* / P55086* / P55085* / F2R like trypsin receptor 1* / Proteinase-activated receptor 2 *ENSDARG0000006885653
f2r / coagulation factor II (thrombin) receptor / P25116* / P30558* / Proteinase-activated receptor 1 *ENSDARG0000006001232
F2RL3 / si:ch211-132p1.2 / O88634* / Q96RI0* / Proteinase-activated receptor 4 * / F2R like thrombin or trypsin receptor 3*ENSDARG0000007939931
zgc:171965ENSDARG0000007763830
si:dkey-163m14.6ENSDARG0000009004130
si:dkey-163m14.2ENSDARG0000005950729
si:dkey-163m14.7ENSDARG0000008623629
si:dkey-163m14.10ENSDARG0000008626229
si:dkey-163m14.4ENSDARG0000008746929
p2ry8 / P2Y receptor family member 8 / Q86VZ1*ENSDARG0000005556025
CABZ01071020.1 / F2RL2* / O00254* / coagulation factor II thrombin receptor like 2*ENSDARG0000007947225
gpr4 / G protein-coupled receptor 4 / P46093* / Q8BUD0*ENSDARG0000007947924
f2rl2 / coagulation factor II (thrombin) receptor-like 2 / O00254*ENSDARG0000009052422
zgc:171579ENSDARG0000003923421
gpr65 / G protein-coupled receptor 65 / Q8IYL9*ENSDARG0000004595719
si:dkey-211g8.7 / FFAR3* / GPR42* / FFAR2* / Q8VCK6* / O15529* / O15552* / Q3UFD7* / O14843* / free fatty acid receptor 2* / free fatty acid receptor 3* / G protein-coupled receptor 42 (gen...ENSDARG0000005853519
gpr184 / G protein-coupled receptor 184ENSDARG0000010291219
si:dkey-211g8.6 / FFAR3* / GPR42* / FFAR2* / Q8VCK6* / O15529* / O15552* / Q3UFD7* / O14843* / free fatty acid receptor 2* / free fatty acid receptor 3* / G protein-coupled receptor 42 (gen...ENSDARG0000006308818
CU855821.1 / GPR42* / FFAR2* / FFAR3* / O15552* / O14843* / O15529* / free fatty acid receptor 2* / free fatty acid receptor 3* / G protein-coupled receptor 42 (gene/pseudogene)*ENSDARG0000007966118
si:dkey-211g8.9 / FFAR1* / O14842* / Q76JU9* / free fatty acid receptor 1*ENSDARG0000008782818


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002281  Protease-activated receptor 2
 IPR003912  Protease-activated receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IBA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IBA
 biological_processGO:0070493 thrombin-activated receptor signaling pathway IEA
 biological_processGO:0097755 positive regulation of blood vessel diameter IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA
 molecular_functionGO:0015057 thrombin-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000036041 f2 / coagulation factor II (thrombin) / P00734* / P19221* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / complex / reaction






 

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