ENSDARG00000078688


Danio rerio

Features
Gene ID: ENSDARG00000078688
  
Biological name :frs3
  
Synonyms : fibroblast growth factor receptor substrate 3 / frs3
  
Possible biological names infered from orthology : O43559 / Q91WJ0
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 40587551
Gene end: 40606273
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000146396
Ensembl peptide - ENSDARP00000129472
Ensembl peptide - ENSDARP00000156127
NCBI entrez gene - 100330147     See in Manteia.
RefSeq - XM_002662499
swissprot - E7F020
ZFIN ID - ZDB-GENE-131121-119
Ensembl - ENSDARG00000078688
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FRS3ENSGALG00000003447Gallus gallus
 FRS3ENSG00000137218Homo sapiens
 Frs3ENSMUSG00000023266Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
frs2a / fibroblast growth factor receptor substrate 2a / FRS2* / Q8C180* / Q8WU20* / fibroblast growth factor receptor substrate 2*ENSDARG0000004587337
frs2b / fibroblast growth factor receptor substrate 2b / FRS2* / Q8C180* / Q8WU20* / fibroblast growth factor receptor substrate 2*ENSDARG0000003735334


Protein motifs (from Interpro)
Interpro ID Name
 IPR002404  IRS-type PTB domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
FRS-mediated FGFR1 signaling
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
RAF/MAP kinase cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007356 fgf20a / fibroblast growth factor 20a / FGF20* / Q9NP95* / Q9ESL9* / fibroblast growth factor 20*  / complex / reaction
 ENSDARG00000004782 fgfr3 / fibroblast growth factor receptor 3 / P22607*  / complex / reaction
 ENSDARG00000011027 fgfr1a / Q90Z00 / fibroblast growth factor receptor 1a / FGFR1* / P11362* / P16092* / fibroblast growth factor receptor 1*  / complex / reaction
 ENSDARG00000030932 fgf10a / fibroblast growth factor 10a / FGF10* / O35565* / O15520* / fibroblast growth factor 10*  / complex / reaction
 ENSDARG00000011190 fgfr1b / fibroblast growth factor receptor 1b / FGFR1* / P16092* / P11362* / fibroblast growth factor receptor 1*  / complex / reaction
 ENSDARG00000043962 fgf18b / fibroblast growth factor 18b / FGF18* / O89101* / O76093* / fibroblast growth factor 18*  / complex / reaction
 ENSDARG00000020334 ptpn11a / protein tyrosine phosphatase, non-receptor type 11, a / PTPN11* / P35235* / Q06124* / Tyrosine-protein phosphatase non-receptor type 11 * / protein tyrosine phosphatase, non-recep...  / complex / reaction
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex / reaction
 ENSDARG00000076294 klb / klotho beta / Q86Z14* / Q99N32* / Beta-klotho *  / complex / reaction
 ENSDARG00000076510 fgf22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*  / complex / reaction
 ENSDARG00000079862 kl / klotho / O35082* / Q9UEF7* / Klotho Klotho peptide*  / complex / reaction
 ENSDARG00000069105 fgfr4 / fibroblast growth factor receptor 4 / P22455*  / complex / reaction
 ENSDARG00000086070 fgf20b / fibroblast growth factor 20b / FGF20* / Q9NP95* / Q9ESL9* / fibroblast growth factor 20*  / complex / reaction
 ENSDARG00000005651 hrasb / -Ha-ras Harvey rat sarcoma viral oncogene homolog b / HRAS* / P01112* / Q61411* / HRas proto-oncogene, GTPase* / GTPase HRas GTPase HRas, N-terminally processed*  / reaction
 ENSDARG00000038225 nras / NRAS proto-oncogene, GTPase / P01111* / neuroblastoma ras oncogene*  / reaction
 ENSDARG00000059387 fgf7 / fibroblast growth factor 7 / P21781*  / complex / reaction
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex / reaction
 ENSDARG00000100475 fgf10b / fibroblast growth factor 10b / FGF10* / O15520* / fibroblast growth factor 10*  / complex / reaction
 ENSDARG00000098663 fgf19 / fibroblast growth factor 19 / Fgf15* / O95750* / O35622* / Fibroblast growth factor 15 *  / complex / reaction
 ENSDARG00000102778 fgf17 / Q6SJP8 / fibroblast growth factor 17 / O60258* / P63075*  / complex / reaction
 ENSDARG00000101540 fgf3 / P48802 / fibroblast growth factor 3 / P11487*  / complex / reaction






 

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