ENSDARG00000078904


Danio rerio

Features
Gene ID: ENSDARG00000078904
  
Biological name :brd4
  
Synonyms : brd4 / bromodomain containing 4 / F1R5H6
  
Possible biological names infered from orthology : Bromodomain-containing protein 4 / O60885 / Q9ESU6
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 53116172
Gene end: 53224280
  
Corresponding Affymetrix probe sets: Dr.11086.1.A1_at (Zebrafish Array)   Dr.11086.2.S1_at (Zebrafish Array)   DrAffx.2.49.A1_at (Zebrafish Array)   DrAffx.2.74.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000101616
Ensembl peptide - ENSDARP00000104162
swissprot - A0A140TAU4
swissprot - F1R5H6
ZFIN ID - ZDB-GENE-030131-267
Ensembl - ENSDARG00000078904
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BRD4ENSG00000141867Homo sapiens
 Brd4ENSMUSG00000024002Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
brdt / bromodomain, testis-specific / Q91Y44* / Q58F21* / bromodomain testis associated* / Bromodomain testis-specific protein *ENSDARG0000010280231
brd3a / bromodomain containing 3a / BRD3* / Q8K2F0* / Q15059* / bromodomain containing 3* / Bromodomain-containing protein 3 *ENSDARG0000000652726
brd2a / bromodomain containing 2a / BRD2* / Q7JJ13* / P25440* / bromodomain containing 2* / Bromodomain-containing protein 2 *ENSDARG0000002228026
brd3b / bromodomain containing 3b / BRD3* / Q8K2F0* / Q15059* / bromodomain containing 3* / Bromodomain-containing protein 3 *ENSDARG0000010012925
ep300b / E1A binding protein p300 b / EP300* / Q09472* / B2RWS6* / E1A binding protein p300* / Histone acetyltransferase p300 *ENSDARG0000006110816
ep300a / E1A binding protein p300 a / EP300* / Q09472* / B2RWS6* / E1A binding protein p300* / Histone acetyltransferase p300 *ENSDARG0000010066616
crebbpb / CREB binding protein b / CREBBP* / Q92793* / CREB binding protein*ENSDARG0000011245216
crebbpa / CREB binding protein a / CREBBP* / Q92793* / CREB binding protein*ENSDARG0000010460915
baz2ba / bromodomain adjacent to zinc finger domain, 2Ba / BAZ2B* / Q9UIF8* / bromodomain adjacent to zinc finger domain 2B*ENSDARG000000577829
baz2a / bromodomain adjacent to zinc finger domain, 2A / Q9UIF9*ENSDARG000001029749
brd2b / bromodomain containing 2bENSDARG000000460878
baz1a / bromodomain adjacent to zinc finger domain, 1A / O88379* / Q9NRL2* / Bromodomain adjacent to zinc finger domain protein 1A *ENSDARG000000997457
baz1b / bromodomain adjacent to zinc finger domain, 1B / Q9UIG0* / Q9Z277* / Tyrosine-protein kinase BAZ1B *ENSDARG000001028326
baz1a / bromodomain adjacent to zinc finger domain, 1A / O88379* / Q9NRL2* / Bromodomain adjacent to zinc finger domain protein 1A *ENSDARG000000632332


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR018359  Bromodomain, conserved site
 IPR027353  NET domain
 IPR031354  Bromodomain protein 4, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002574 thrombocyte differentiation IMP
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter ISS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0050727 regulation of inflammatory response ISS
 biological_processGO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain ISS
 cellular_componentGO:0000793 condensed chromosome IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0002039 p53 binding ISS
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0070577 lysine-acetylated histone binding TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009323 thrombocyte thrombocyte decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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