ENSDARG00000078970


Danio rerio

Features
Gene ID: ENSDARG00000078970
  
Biological name :il7r
  
Synonyms : il7r / interleukin 7 receptor
  
Possible biological names infered from orthology : Interleukin-7 receptor subunit alpha / P16871 / P16872
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 22429509
Gene end: 22435957
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000119705
NCBI entrez gene - 100134973     See in Manteia.
RefSeq - NM_001113507
RefSeq Peptide - NP_001106979
swissprot - E9QDP8
ZFIN ID - ZDB-GENE-080110-7
Ensembl - ENSDARG00000078970
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL7RENSGALG00000013372Gallus gallus
 IL7RENSG00000168685Homo sapiens
 Il7rENSMUSG00000003882Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003531  Short hematopoietin receptor, family 1, conserved site
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0022010 central nervous system myelination IMP
 biological_processGO:0022011 myelination in peripheral nervous system IMP
 biological_processGO:0033077 T cell differentiation in thymus IMP
 biological_processGO:0046427 positive regulation of JAK-STAT cascade IMP
 biological_processGO:0048538 thymus development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-7 signaling
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord oligodendrocyte decreased amount , abnormal
Show

 ZFA:0001078 thymus thymus decreased size , abnormal
thymus cellularity , abnormal
thymus has fewer parts of type pro-T cell , abnormal
thymus decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased amount , abnormal
Show

 ZFA:0001115 trunk trunk curved ventral , abnormal
Show

 ZFA:0001469 lateral line lateral line myelinating Schwann cell decreased amount , abnormal
lateral line myelinating Schwann cell absent , abnormal
Show

 ZFA:0009350 pro-T cell pro-T cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010252 jak3 / Janus kinase 3 (a protein tyrosine kinase, leukocyte) / P52333* / Janus kinase 3*  / complex
 ENSDARG00000020625 jak1 / Janus kinase 1 / P23458*  / complex
 ENSDARG00000068858 il2rga / interleukin 2 receptor, gamma a / IL2RG* / P34902* / P31785* / Gm20489* / AL590764.2* / interleukin 2 receptor subunit gamma* / Cytokine receptor common subunit gamma *  / complex
 ENSDARG00000054087 irs1 / insulin receptor substrate 1 / P35568*  / complex
 ENSDARG00000075282 irs2b / insulin receptor substrate 2b / IRS2* / Irs3* / P81122* / Q9Y4H2* / insulin receptor substrate 2*  / complex
 ENSDARG00000053702 il2rgb / interleukin 2 receptor, gamma b / IL2RG* / P34902* / P31785* / Gm20489* / AL590764.2* / interleukin 2 receptor subunit gamma* / Cytokine receptor common subunit gamma *  / complex






 

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