ENSDARG00000079420


Danio rerio

Features
Gene ID: ENSDARG00000079420
  
Biological name :dpp4
  
Synonyms : dipeptidyl-peptidase 4 / dpp4
  
Possible biological names infered from orthology : Dipeptidyl peptidase 4 Dipeptidyl peptidase 4 membrane form Dipeptidyl peptidase 4 soluble form / FAP / fibroblast activation protein alpha / P27487 / P28843 / P97321 / Prolyl endopeptidase FAP Antiplasmin-cleaving enzyme FAP, soluble form / Q12884
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 11628438
Gene end: 11648322
  
Corresponding Affymetrix probe sets: DrAffx.2.100.A1_at (Zebrafish Array)   DrAffx.2.100.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000098701
Ensembl peptide - ENSDARP00000156312
NCBI entrez gene - 100301982     See in Manteia.
swissprot - B5DDZ4
ZFIN ID - ZDB-GENE-081104-277
Ensembl - ENSDARG00000079420
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DPP4ENSGALG00000042452Gallus gallus
 FAPENSGALG00000011099Gallus gallus
 DPP4ENSG00000197635Homo sapiens
 FAPENSG00000078098Homo sapiens
 Dpp4ENSMUSG00000035000Mus musculus
 FapENSMUSG00000000392Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fap / fibroblast activation protein, alpha / DPP4* / Q12884* / P27487* / P28843* / P97321* / dipeptidyl peptidase 4* / Prolyl endopeptidase FAP Antiplasmin-cleaving enzyme FAP, soluble form...ENSDARG0000007846859
dpp6a / dipeptidyl-peptidase 6a / DPP6* / Q9Z218* / P42658* / dipeptidyl peptidase like 6* / Dipeptidyl aminopeptidase-like protein 6 *ENSDARG0000007682631
dpp6b / dipeptidyl-peptidase 6b / DPP6* / Q9Z218* / P42658* / dipeptidyl peptidase like 6* / Dipeptidyl aminopeptidase-like protein 6 *ENSDARG0000002474430
CR381531.2 / DPP10* / Q8N608* / dipeptidyl peptidase like 10*ENSDARG0000010476729
dpp9 / dipeptidyl-peptidase 9 / Q86TI2* / Q8BVG4*ENSDARG0000005260622


Protein motifs (from Interpro)
Interpro ID Name
 IPR001375  Peptidase S9, prolyl oligopeptidase, catalytic domain
 IPR002469  Dipeptidylpeptidase IV, N-terminal domain
 IPR002471  Peptidase S9, serine active site
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000079296 gcga / glucagon a / GCG* / P01275* / P55095* / glucagon* / Glucagon Glicentin Glicentin-related polypeptide Oxyntomodulin Glucagon Glucagon-like peptide 1 Glucagon-like peptide 1(7-37) Gluc...  / reaction
 ENSDARG00000040907 gcgb / glucagon b / GCG* / P01275* / P55095* / glucagon* / Glucagon Glicentin Glicentin-related polypeptide Oxyntomodulin Glucagon Glucagon-like peptide 1 Glucagon-like peptide 1(7-37) Gluc...  / reaction






 

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