ENSDARG00000088048


Danio rerio

Features
Gene ID: ENSDARG00000088048
  
Biological name :fgf18a
  
Synonyms : fgf18a / fibroblast growth factor 18a
  
Possible biological names infered from orthology : FGF18 / fibroblast growth factor 18 / O76093 / O89101
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 2487672
Gene end: 2536342
  
Corresponding Affymetrix probe sets: Dr.25473.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000106596
Ensembl peptide - ENSDARP00000132361
swissprot - A0A0R4IBT1
swissprot - F1QKX4
ZFIN ID - ZDB-GENE-030714-1
Ensembl - ENSDARG00000088048
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FGF18ENSGALG00000002203Gallus gallus
 FGF18ENSG00000156427Homo sapiens
 Fgf18ENSMUSG00000057967Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fgf18b / fibroblast growth factor 18b / FGF18* / O89101* / O76093* / fibroblast growth factor 18*ENSDARG0000004396268
fgf24 / fibroblast growth factor 24ENSDARG0000003767749
fgf8a / O57341 / fibroblast growth factor 8aENSDARG0000000339944
fgf17 / Q6SJP8 / fibroblast growth factor 17 / O60258* / P63075*ENSDARG0000010277844
fgf8b / Q805B2 / fibroblast growth factor 8 bENSDARG0000003961542


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028289  Fibroblast growth factor 18


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR4 ligand binding and activation
FGFR3b ligand binding and activation
FGFR3c ligand binding and activation
FGFR2c ligand binding and activation
Phospholipase C-mediated cascade; FGFR2
Phospholipase C-mediated cascade; FGFR3
Phospholipase C-mediated cascade; FGFR4
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
SHC-mediated cascade:FGFR3
FRS-mediated FGFR3 signaling
PI-3K cascade:FGFR3
FRS-mediated FGFR4 signaling
SHC-mediated cascade:FGFR4
PI-3K cascade:FGFR4
Negative regulation of FGFR2 signaling
Negative regulation of FGFR3 signaling
Negative regulation of FGFR4 signaling
FGFRL1 modulation of FGFR1 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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