ENSDARG00000088590


Danio rerio

Features
Gene ID: ENSDARG00000088590
  
Biological name :pxna
  
Synonyms : paxillin a / pxna
  
Possible biological names infered from orthology : P49023 / paxillin / PXN / Q8VI36
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 6670945
Gene end: 6718120
  
Corresponding Affymetrix probe sets: Dr.9446.1.A1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000104565
Ensembl peptide - ENSDARP00000148251
NCBI entrez gene - 399546     See in Manteia.
RefSeq - NM_201588
RefSeq Peptide - NP_963882
swissprot - F1R1J6
ZFIN ID - ZDB-GENE-040105-1
Ensembl - ENSDARG00000088590
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PXNENSGALG00000007247Gallus gallus
 PXNENSG00000089159Homo sapiens
 PxnENSMUSG00000029528Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pxnb / paxillin b / PXN* / P49023* / paxillin*ENSDARG0000006076672
lpxn / leupaxin / O60711* / Q99N69*ENSDARG0000007931534
ldb3a / LIM domain binding 3a / LDB3* / O75112* / Q9JKS4* / LIM domain binding 3* / LIM domain-binding protein 3 *ENSDARG0000005632218
pdlim5a / PDZ and LIM domain 5a / PDLIM5* / Q8CI51* / Q96HC4* / PDZ and LIM domain 5* / PDZ and LIM domain protein 5 *ENSDARG0000010177717
pdlim5b / PDZ and LIM domain 5b / PDLIM5* / Q96HC4* / PDZ and LIM domain 5*ENSDARG0000002760016
CABZ01078593.1 / Q3TJD7* / PDLIM7* / Q9NR12* / PDZ and LIM domain 7* / PDZ and LIM domain protein 7 *ENSDARG0000010385416
lims1 / LIM and senescent cell antigen-like domains 1 / LIMS3* / LIMS4* / P48059* / P0CW19* / P0CW20* / AC013271.1* / AC112229.3* / LIM zinc finger domain containing 4* / LIM zinc finger do...ENSDARG0000002698513
fhl5 / four and a half LIM domains 5 / Q5TD97* / Q9WTX7* / Four and a half LIM domains protein 5 *ENSDARG0000001480512
lims2 / LIM and senescent cell antigen-like domains 2 / LIMS3* / LIMS4* / LIMS1* / P48059* / P0CW19* / P0CW20* / AC013271.1* / AC112229.3* / LIM zinc finger domain containing 3* / LIM zinc ...ENSDARG0000001497612
fhl3a / four and a half LIM domains 3a / FHL3* / Q13643* / Q9R059* / four and a half LIM domains 3* / Four and a half LIM domains protein 3 *ENSDARG0000003464312
fhl2a / four and a half LIM domains 2a / FHL2* / O70433* / Q14192* / four and a half LIM domains 2* / Four and a half LIM domains protein 2 *ENSDARG0000004201812
fhl1b / four and a half LIM domains 1b / FHL1* / Fhl4* / Q13642* / P97447* / four and a half LIM domains 1* / Four and a half LIM domains protein 1 *ENSDARG0000005665312
fhl2b / four and a half LIM domains 2b / FHL2* / O70433* / Q14192* / four and a half LIM domains 2* / Four and a half LIM domains protein 2 *ENSDARG0000000399111
fhl1a / four and a half LIM domains 1a / FHL1* / Fhl4* / Q13642* / P97447* / four and a half LIM domains 1* / Four and a half LIM domains protein 1 *ENSDARG0000007149811
fhl3b / four and a half LIM domains 3b / FHL3* / Q13643* / Q9R059* / four and a half LIM domains 3* / Four and a half LIM domains protein 3 *ENSDARG0000010431511
ldb3b / LIM domain binding 3bENSDARG000000999744


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type
 IPR001904  Paxillin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IEP
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007519 skeletal muscle tissue development IGI
 biological_processGO:0043009 chordate embryonic development IEP
 biological_processGO:0061055 myotome development IGI
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
GAB1 signalosome
VEGFA-VEGFR2 Pathway
Smooth Muscle Contraction
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart decreased functionality , abnormal
heart focal adhesion absent , abnormal
Show

 ZFA:0000610 vertical myoseptum vertical myoseptum decreased amount , abnormal
Show

 ZFA:0001056 myotome myotome malformed , abnormal
myotome muscle tendon junction decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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