ENSDARG00000088634


Danio rerio

Features
Gene ID: ENSDARG00000088634
  
Biological name :adcy1b
  
Synonyms : adcy1b / adenylate cyclase 1b
  
Possible biological names infered from orthology : ADCY1 / adenylate cyclase 1 / Adenylate cyclase type 1 / O88444 / Q08828
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 136346
Gene end: 155270
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000107181
Ensembl peptide - ENSDARP00000128986
swissprot - F1R914
swissprot - X1WFI2
ZFIN ID - ZDB-GENE-100805-1
Ensembl - ENSDARG00000088634
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADCY1ENSGALG00000031170Gallus gallus
 ADCY1ENSG00000164742Homo sapiens
 Adcy1ENSMUSG00000020431Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adcy1a / adenylate cyclase 1a / ADCY1* / Q08828* / O88444* / adenylate cyclase 1* / Adenylate cyclase type 1 *ENSDARG0000006902673
adcy6b / adenylate cyclase 6b / ADCY6* / O43306* / adenylate cyclase 6*ENSDARG0000002779741
adcy6a / adenylate cyclase 6a / ADCY6* / O43306* / adenylate cyclase 6*ENSDARG0000006144541
adcy5 / adenylate cyclase 5 / O95622* / P84309* / Adenylate cyclase type 5 *ENSDARG0000009134241
adcy8 / adenylate cyclase 8 (brain) / P97490* / P40145* / adenylate cyclase 8* / Adenylate cyclase type 8 *ENSDARG0000003178338
adcy2b / adenylate cyclase 2b (brain) / ADCY2* / Q08462* / adenylate cyclase 2*ENSDARG0000001458837
si:ch211-132f19.7ENSDARG0000004314137
si:dkey-206f10.1ENSDARG0000003283836
adcy2a / adenylate cyclase 2a / ADCY2* / Q08462* / adenylate cyclase 2*ENSDARG0000005839236
adcy7 / adenylate cyclase 7 / P51828* / P51829* / Adenylate cyclase type 7 *ENSDARG0000006007036
adcy3a / adenylate cyclase 3a / ADCY3* / O60266* / adenylate cyclase 3*ENSDARG0000007714535
adcy3b / adenylate cyclase 3b / ADCY3* / Q8VHH7* / O60266* / adenylate cyclase 3* / Adenylate cyclase type 3 *ENSDARG0000001743732
adcy9 / adenylate cyclase 9 / O60503* / P51830* / Adenylate cyclase type 9 *ENSDARG0000010086929
CR339059.1 / ADCY9* / O60503* / adenylate cyclase 9*ENSDARG0000010384714


Protein motifs (from Interpro)
Interpro ID Name
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR009398  Adenylate cyclase, conserved domain
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR029787  Nucleotide cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006171 cAMP biosynthetic process IEA
 biological_processGO:0006182 cGMP biosynthetic process IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007605 sensory perception of sound IMP
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0016199 axon midline choice point recognition IGI
 biological_processGO:0031290 retinal ganglion cell axon guidance IGI
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity IBA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA


Pathways (from Reactome)
Pathway description
PKA activation
Adenylate cyclase activating pathway
Adenylate cyclase inhibitory pathway
G alpha (z) signalling events
CREB phosphorylation through the activation of Adenylate Cyclase
Hedgehog off state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis curved , abnormal
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 ZFA:0009121 auditory receptor cell auditory receptor cell decreased functionality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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