ENSDARG00000099365


Danio rerio

Features
Gene ID: ENSDARG00000099365
  
Biological name :evx1
  
Synonyms : even-skipped homeobox 1 / evx1
  
Possible biological names infered from orthology : Homeobox even-skipped homolog protein 1 / P23683 / P49640
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 19717971
Gene end: 19871211
  
Corresponding Affymetrix probe sets: Dr.8101.1.S1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000133433
swissprot - Q9DD27
ZFIN ID - ZDB-GENE-980526-364
Ensembl - ENSDARG00000099365
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EVX1ENSGALG00000037310Gallus gallus
 EVX1ENSG00000106038Homo sapiens
 Evx1ENSMUSG00000005503Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
evx1 / even-skipped homeobox 1 / P23683* / P49640* / Homeobox even-skipped homolog protein 1 *ENSDARG00000100087100
evx2 / even-skipped homeobox 2ENSDARG0000005925563
eve1 / even-skipped-like1ENSDARG0000005601234
mnx1 / motor neuron and pancreas homeobox 1 / P50219* / Q9QZW9*ENSDARG0000003598419
meox2b / mesenchyme homeobox 2b / MEOX2* / P50222* / P32443* / mesenchyme homeobox 2* / Homeobox protein MOX-2 *ENSDARG0000006181818
nkx1.2la / NK1 transcription factor related 2-like,a / Q9UD57* / NKX1-2* / P42580* / NK1 homeobox 2* / NK1 transcription factor-related protein 2 *ENSDARG0000000635017
mnx2b / motor neuron and pancreas homeobox 2bENSDARG0000003035017
meox2a / mesenchyme homeobox 2a / MEOX2* / P50222* / P32443* / mesenchyme homeobox 2* / Homeobox protein MOX-2 *ENSDARG0000004091117
ved / ventrally expressed dharma/bozozok antagonistENSDARG0000010238917
gbx2 / gastrulation brain homeobox 2 / P48031* / P52951* / Homeobox protein GBX-2 *ENSDARG0000000293316
mnx2a / motor neuron and pancreas homeobox 2aENSDARG0000004210616
nkx1.2lb / NK1 transcription factor related 2-like,b / Q15270* / NKX1-1* / NK1 homeobox 1* / NK1 transcription factor-related protein 1 *ENSDARG0000009942716
meox1 / F1Q4R9 / mesenchyme homeobox 1ENSDARG0000000789115
gbx1 / gastrulation brain homeobox 1 / P82976* / Q14549* / Homeobox protein GBX-1 *ENSDARG0000007141815
vox / ventral homeobox / VENTX* / O95231* / VENT homeobox*ENSDARG0000009976115
pnx / F1R2J1 / posterior neuron-specific homeoboxENSDARG0000002589914
vent / ventral expressed homeobox / VENTX* / O95231* / VENT homeobox*ENSDARG0000010048314


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0033334 fin morphogenesis IMP
 biological_processGO:0072498 embryonic skeletal joint development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord has fewer parts of type glutamatergic neuron , abnormal
spinal cord has extra parts of type glycinergic neuron , abnormal
spinal cord cell decreased distribution , abnormal
spinal cord cell decreased amount , abnormal
Show

 ZFA:0000778 spinal cord interneuron spinal cord interneuron absent , abnormal
spinal cord interneuron decreased distribution , abnormal
spinal cord interneuron glutamatergic neuron absent , abnormal
spinal cord interneuron GABAergic neuron mislocalised , abnormal
spinal cord interneuron glutamatergic neuron mislocalised , abnormal
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 ZFA:0001058 caudal fin caudal fin deformed , abnormal
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 ZFA:0001550 caudal fin lepidotrichium caudal fin lepidotrichium undivided , abnormal
caudal fin lepidotrichium joint absent , abnormal
caudal fin lepidotrichium spatial pattern , abnormal
caudal fin lepidotrichium broken , abnormal
caudal fin lepidotrichium lacks parts or has fewer parts of type lepidotrichium joint , abnormal
Show

 ZFA:0001551 pectoral fin lepidotrichium pectoral fin lepidotrichium undivided , abnormal
pectoral fin lepidotrichium joint absent , abnormal
Show

 ZFA:0001554 lepidotrichium lepidotrichium undivided , abnormal
lepidotrichium joint absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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