ENSDARG00000100374


Danio rerio

Features
Gene ID: ENSDARG00000100374
  
Biological name :txnrd3
  
Synonyms : thioredoxin reductase 3 / txnrd3
  
Possible biological names infered from orthology : Q86VQ6
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 1161224
Gene end: 1187749
  
Corresponding Affymetrix probe sets: Dr.25282.1.S1_at (Zebrafish Array)   Dr.4986.1.S1_at (Zebrafish Array)   NM_183072_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000135844
Ensembl peptide - ENSDARP00000153083
NCBI entrez gene - 352924     See in Manteia.
RefSeq - NM_183072
RefSeq Peptide - NP_898895
swissprot - Q7T2C8
ZFIN ID - ZDB-GENE-030327-3
Ensembl - ENSDARG00000100374
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TXNRD3ENSGALG00000039363Gallus gallus
 Q86VQ6ENSG00000197763Homo sapiens
 Txnrd3ENSMUSG00000000811Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
txnrd2.2 / thioredoxin reductase 2, tandem duplicate 2 / Q9NNW7* / TXNRD2* / thioredoxin reductase 2*ENSDARG0000007592346
gsr / glutathione reductase / P47791* / P00390* / glutathione-disulfide reductase* / Glutathione reductase, mitochondrial *ENSDARG0000001923622
txnrd2.1 / thioredoxin reductase 2, tandem duplicate 1 / Q9NNW7* / TXNRD2* / thioredoxin reductase 2*ENSDARG0000009447018


Protein motifs (from Interpro)
Interpro ID Name
 IPR002109  Glutaredoxin
 IPR004099  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
 IPR006338  Thioredoxin/glutathione reductase selenoprotein
 IPR011767  Glutaredoxin active site
 IPR011899  Glutaredoxin, eukaryotic/virial
 IPR012336  Thioredoxin-like fold
 IPR012999  Pyridine nucleotide-disulphide oxidoreductase, class I, active site
 IPR016156  FAD/NAD-linked reductase, dimerisation domain superfamily
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000305 response to oxygen radical IBA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0045454 cell redox homeostasis IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005739 mitochondrion IBA
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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