ENSDARG00000100494


Danio rerio

Features
Gene ID: ENSDARG00000100494
  
Biological name :pbx1a
  
Synonyms : pbx1a / pre-B-cell leukemia homeobox 1a
  
Possible biological names infered from orthology : P40424 / P41778 / PBX1 / PBX homeobox 1 / Pre-B-cell leukemia transcription factor 1
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 18698388
Gene end: 18830794
  
Corresponding Affymetrix probe sets: Dr.21042.1.S1_at (Zebrafish Array)   Dr.21071.1.S1_s_at (Zebrafish Array)   Dr.8172.1.S1_at (Zebrafish Array)   NM_131615_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000136221
Ensembl peptide - ENSDARP00000138945
NCBI entrez gene - 58138     See in Manteia.
RefSeq - NM_131615
RefSeq Peptide - NP_571690
swissprot - Q9I9B6
swissprot - Q9I9B7
ZFIN ID - ZDB-GENE-000405-1
Ensembl - ENSDARG00000100494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PBX1ENSGALG00000003429Gallus gallus
 PBX1ENSG00000185630Homo sapiens
 Pbx1ENSMUSG00000052534Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pbx1b / pre-B-cell leukemia homeobox 1b / PBX1* / P40424* / PBX homeobox 1*ENSDARG0000010113194
pbx3a / pre-B-cell leukemia homeobox 3a / PBX3* / P40426* / O35317* / PBX homeobox 3* / Pre-B-cell leukemia transcription factor 3 *ENSDARG0000008926274
pbx3b / pre-B-cell leukemia homeobox 3b / PBX3* / P40426* / O35317* / PBX homeobox 3* / Pre-B-cell leukemia transcription factor 3 *ENSDARG0000001361565
pbx2 / pre-B-cell leukemia homeobox 2 / O35984* / P40425* / PBX homeobox 2*ENSDARG0000001971763
pbx4 / pre-B-cell leukemia transcription factor 4 / Q99NE9* / Q9BYU1* / PBX homeobox 4* / Mus musculus pre B cell leukemia homeobox 4 (Pbx4), transcript variant 4, mRNA.*ENSDARG0000005215063


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR005542  PBX
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030223 neutrophil differentiation IMP
 biological_processGO:0048795 swim bladder morphogenesis IMP
 biological_processGO:0060216 definitive hemopoiesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder physical object quality , abnormal
swim bladder morphology , abnormal
Show

 ZFA:0000094 blood island blood island neutrophil decreased amount , abnormal
Show

 ZFA:0000254 pancreas primordium pancreas primordium physical object quality , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch physical object quality , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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