ENSDARG00000101251


Danio rerio

Features
Gene ID: ENSDARG00000101251
  
Biological name :ldha
  
Synonyms : lactate dehydrogenase A4 / ldha / Q9PVK5
  
Possible biological names infered from orthology : lactate dehydrogenase A / lactate dehydrogenase A like 6A / lactate dehydrogenase A like 6B / lactate dehydrogenase C / LDHAL6A / LDHAL6B / LDHC / L-lactate dehydrogenase A chain / P00338 / P00342 / P06151 / P07864 / Q6ZMR3 / Q9BYZ2
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 25123385
Gene end: 25131755
  
Corresponding Affymetrix probe sets: Dr.4212.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000137433
Ensembl peptide - ENSDARP00000140963
NCBI entrez gene - 30496     See in Manteia.
swissprot - Q9PVK5
ZFIN ID - ZDB-GENE-991026-5
Ensembl - ENSDARG00000101251
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LDHAENSGALG00000006300Gallus gallus
 LDHAENSG00000134333Homo sapiens
 LDHCENSG00000166796Homo sapiens
 Q6ZMR3ENSG00000166800Homo sapiens
 Q9BYZ2ENSG00000171989Homo sapiens
 LdhaENSMUSG00000063229Mus musculus
 Ldhal6bENSMUSG00000101959Mus musculus
 LdhcENSMUSG00000030851Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ldhba / Q9PVK4 / lactate dehydrogenase Ba / LDHB* / P07195* / P16125* / lactate dehydrogenase B* / L-lactate dehydrogenase B chain *ENSDARG0000001964472
ldhbb / Q6DGK2 / lactate dehydrogenase Bb / LDHB* / P07195* / P16125* / lactate dehydrogenase B* / L-lactate dehydrogenase B chain *ENSDARG0000007107672
uevld / Q6DBY5 / UEV and lactate/malate dehyrogenase domains / Q3U1V6* / Q8IX04*ENSDARG0000000926636


Protein motifs (from Interpro)
Interpro ID Name
 IPR001236  Lactate/malate dehydrogenase, N-terminal
 IPR001557  L-lactate/malate dehydrogenase
 IPR011304  L-lactate dehydrogenase
 IPR015955  Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
 IPR016040  NAD(P)-binding domain
 IPR018177  L-lactate dehydrogenase, active site
 IPR022383  Lactate/malate dehydrogenase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004459 L-lactate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019644 ldhba / Q9PVK4 / lactate dehydrogenase Ba / LDHB* / P07195* / P16125* / lactate dehydrogenase B* / L-lactate dehydrogenase B chain *  / complex
 ENSDARG00000071076 ldhbb / Q6DGK2 / lactate dehydrogenase Bb / LDHB* / P07195* / P16125* / lactate dehydrogenase B* / L-lactate dehydrogenase B chain *  / complex
 ENSDARG00000101251 ldha / Q9PVK5 / lactate dehydrogenase A4 / LDHC* / P07864* / Q9BYZ2* / P00338* / P00342* / P06151* / Q6ZMR3* / LDHAL6A* / LDHAL6B* / lactate dehydrogenase C* / lactate dehydrogenase A* / la...  / complex






 

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