ENSDARG00000101471


Danio rerio

Features
Gene ID: ENSDARG00000101471
  
Biological name :fgd4a
  
Synonyms : fgd4a / FYVE, RhoGEF and PH domain containing 4a
  
Possible biological names infered from orthology : FGD4 / FYVE, RhoGEF and PH domain containing 4 / FYVE, RhoGEF and PH domain-containing protein 4 / Q91ZT5 / Q96M96
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 12147971
Gene end: 12229524
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000135370
Ensembl peptide - ENSDARP00000138561
NCBI entrez gene - 556216     See in Manteia.
RefSeq - NM_001177933
RefSeq Peptide - NP_001171404
swissprot - F1QAA5
swissprot - A0A0J9YJA6
ZFIN ID - ZDB-GENE-050420-347
Ensembl - ENSDARG00000101471
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FGD4ENSGALG00000012932Gallus gallus
 FGD4ENSG00000139132Homo sapiens
 Fgd4ENSMUSG00000022788Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fgd4b / FYVE, RhoGEF and PH domain containing 4b / FGD4* / Q96M96* / FYVE, RhoGEF and PH domain containing 4*ENSDARG0000006024858
fgd1 / FYVE, RhoGEF and PH domain containing 1 / P52734* / P98174* / FYVE, RhoGEF and PH domain-containing protein 1 *ENSDARG0000010040244
fgd6 / FYVE, RhoGEF and PH domain containing 6 / Q69ZL1* / Q6ZV73* / FYVE, RhoGEF and PH domain-containing protein 6 *ENSDARG0000004552825
CABZ01079663.1 / FGD3* / Q5JSP0* / FYVE, RhoGEF and PH domain containing 3*ENSDARG0000009965025
fgd5a / FYVE, RhoGEF and PH domain containing 5a / FGD5* / Q6ZNL6* / FYVE, RhoGEF and PH domain containing 5*ENSDARG0000008880120
fgd5b / FYVE, RhoGEF and PH domain containing 5b / FGD5* / Q6ZNL6* / FYVE, RhoGEF and PH domain containing 5*ENSDARG0000008962214
Q7ZUV1 / plekhf2 / pleckstrin homology domain containing, family F (with FYVE domain) member 2 / Q91WB4* / Q9H8W4* / pleckstrin homology and FYVE domain containing 2* / Pleckstrin homology ...ENSDARG000000211419
plekhf1 / pleckstrin homology domain containing, family F (with FYVE domain) member 1 / Q3TB82* / Q96S99* / pleckstrin homology and FYVE domain containing 1* / Pleckstrin homology domain-co...ENSDARG000001024358


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000306  FYVE zinc finger
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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