ENSDARG00000101752


Danio rerio

Features
Gene ID: ENSDARG00000101752
  
Biological name :plekhg5b
  
Synonyms : pleckstrin homology domain containing, family G (with RhoGef domain) member 5b / plekhg5b
  
Possible biological names infered from orthology : O94827 / pleckstrin homology and RhoGEF domain containing G5 / Pleckstrin homology domain-containing family G member 5 / PLEKHG5 / Q66T02
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 37579107
Gene end: 37720166
  
Corresponding Affymetrix probe sets: Dr.13261.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000141299
NCBI entrez gene - 796404     See in Manteia.
RefSeq - XM_021470028
swissprot - A0A0G2L933
ZFIN ID - ZDB-GENE-090908-6
Ensembl - ENSDARG00000101752
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLEKHG5ENSGALG00000027476Gallus gallus
 O94827ENSG00000171680Homo sapiens
 Q66T02ENSMUSG00000039713Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plekhg5a / pleckstrin homology domain containing, family G (with RhoGef domain) member 5a / O94827* / Q66T02* / PLEKHG5* / pleckstrin homology and RhoGEF domain containing G5* / Pleckstrin ...ENSDARG0000002590252
plekhg6 / pleckstrin homology domain containing, family G (with RhoGef domain) member 6 / Q3KR16* / Q8R0J1* / pleckstrin homology and RhoGEF domain containing G6* / Pleckstrin homology doma...ENSDARG0000008605618
plekhg7 / pleckstrin homology domain containing, family G (with RhoGef domain) member 7 / Q6ZR37* / pleckstrin homology and RhoGEF domain containing G7*ENSDARG0000006285513


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0043534 blood vessel endothelial cell migration IMP
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001052 primordial hindbrain channel primordial hindbrain channel dilated , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel truncated , abnormal
intersegmental vessel morphology , abnormal
Show

 ZFA:0005017 primordial midbrain channel primordial midbrain channel dilated , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel aplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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