ENSDARG00000102142


Danio rerio

Features
Gene ID: ENSDARG00000102142
  
Biological name :ECE2
  
Synonyms : ECE2 / ece2b / si:ch211-117a13.2
  
Possible biological names infered from orthology : EEF1AKMT4-ECE2 / EEF1AKMT4-ECE2 readthrough / endothelin converting enzyme 2 / O60344
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 4172288
Gene end: 4314097
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000135807
Ensembl peptide - ENSDARP00000142275
NCBI entrez gene - 793465     See in Manteia.
RefSeq - NM_001302239
RefSeq Peptide - NP_001289168
swissprot - A0A0H2UKN8
swissprot - A0A024B5K5
swissprot - A0A140LG96
ZFIN ID - ZDB-GENE-131120-140
ZFIN ID - ZDB-GENE-160113-64
Ensembl - ENSDARG00000102142
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000006272Gallus gallus
 ECE2ENSG00000145194Homo sapiens
 O60344ENSG00000284917Homo sapiens
 Ece2ENSMUSG00000022842Mus musculus
 Ece2ENSMUSG00000115293Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ece1 / endothelin converting enzyme 1 / P42892* / Q4PZA2*ENSDARG0000006173761
mmel1 / membrane metallo-endopeptidase-like 1 / Q495T6* / membrane metalloendopeptidase like 1*ENSDARG0000010538938
phex / phosphate regulating endopeptidase homolog, X-linked / P70669* / P78562* / Metalloendopeptidase homolog PEX *ENSDARG0000006236336
ecel1 / endothelin converting enzyme-like 1 / O95672*ENSDARG0000006054932
kel / Kell blood group, metallo-endopeptidase / P23276* / Q9EQF2* / Kell blood group glycoprotein homolog *ENSDARG0000007695021


Protein motifs (from Interpro)
Interpro ID Name
 IPR000718  Peptidase M13
 IPR008753  Peptidase M13, N-terminal domain
 IPR018497  Peptidase M13, C-terminal domain
 IPR024079  Metallopeptidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016486 peptide hormone processing IEA
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0070285 pigment cell development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism decreased life span , ameliorated
whole organism neoplasm increased amount , abnormal
whole organism melanoma increased amount , ameliorated
Show

 ZFA:0009091 melanocyte melanocyte decreased amount , abnormal
melanocyte shape , abnormal
melanocyte decreased pigmentation , abnormal
Show

 ZFA:0009199 iridophore iridophore decreased amount , abnormal
iridophore ridged , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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