ENSMUSG00000022842


Mus musculus

Features
Gene ID: ENSMUSG00000022842
  
Biological name :Ece2
  
Synonyms : Ece2
  
Possible biological names infered from orthology : EEF1AKMT4-ECE2 / EEF1AKMT4-ECE2 readthrough / endothelin converting enzyme 2 / O60344
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B1
Gene start: 20629828
Gene end: 20646485
  
Corresponding Affymetrix probe sets: 10434446 (MoGene1.0st)   1424561_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119693
Ensembl peptide - ENSMUSP00000120239
Ensembl peptide - ENSMUSP00000003898
Ensembl peptide - ENSMUSP00000114039
NCBI entrez gene - 107522     See in Manteia.
MGI - MGI:1101356
RefSeq - XM_017316848
RefSeq - XM_006521695
RefSeq - XM_006521696
RefSeq - XM_006521697
RefSeq - XM_006521698
RefSeq - XM_006521700
RefSeq - XM_011245802
RefSeq - NM_139293
RefSeq - NM_177942
RefSeq - XM_006521691
RefSeq - XM_006521692
RefSeq - XM_006521693
RefSeq - XM_006521694
RefSeq Peptide - NP_808811
RefSeq Peptide - NP_647454
swissprot - E9Q896
swissprot - F6WM66
swissprot - E9Q1S5
swissprot - B2RQR8
Ensembl - ENSMUSG00000022842
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ECE2ENSDARG00000102142Danio rerio
 ENSGALG00000006272Gallus gallus
 ECE2ENSG00000145194Homo sapiens
 O60344ENSG00000284917Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ece2 / O60344* / EEF1AKMT4-ECE2* / EEF1AKMT4-ECE2 readthrough* / endothelin converting enzyme 2*ENSMUSG0000011529399
Ece1 / Q4PZA2 / Endothelin-converting enzyme 1 / P42892*ENSMUSG0000005753061
Ecel1 / Q9JMI0 / Endothelin-converting enzyme-like 1 / O95672*ENSMUSG0000002624737
Mmel1 / membrane metallo-endopeptidase-like 1 / Q495T6* / membrane metalloendopeptidase like 1*ENSMUSG0000005818337
Mme / Q61391 / Neprilysin / P08473* / membrane metalloendopeptidase*ENSMUSG0000002782035
Phex / P70669 / Metalloendopeptidase homolog PEX / P78562* / phosphate regulating endopeptidase homolog X-linked*ENSMUSG0000005745733
Kel / Q9EQF2 / Kell blood group glycoprotein homolog / P23276* / Kell blood group, metallo-endopeptidase*ENSMUSG0000002986628


Protein motifs (from Interpro)
Interpro ID Name
 IPR000718  Peptidase M13
 IPR008753  Peptidase M13, N-terminal domain
 IPR018497  Peptidase M13, C-terminal domain
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR029733  Endothelin-converting enzyme


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016486 peptide hormone processing IEA
 cellular_componentGO:0000139 Golgi membrane ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030658 transport vesicle membrane ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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