ENSDARG00000104149


Danio rerio

Features
Gene ID: ENSDARG00000104149
  
Biological name :rraga
  
Synonyms : Ras-related GTP binding A / rraga
  
Possible biological names infered from orthology : Q5VZM2 / Q6NTA4 / Q7L523 / Q80X95 / Ras related GTP binding B / Ras-related GTP-binding protein A / Ras-related GTP-binding protein B / RRAGB
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 14027427
Gene end: 14094406
  
Corresponding Affymetrix probe sets: Dr.1798.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000131439
Ensembl peptide - ENSDARP00000151097
swissprot - A0A0R4IC95
ZFIN ID - ZDB-GENE-030131-4083
Ensembl - ENSDARG00000104149
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000041226Gallus gallus
 RRAGAENSG00000155876Homo sapiens
 RRAGBENSG00000083750Homo sapiens
 RragaENSMUSG00000070934Mus musculus
 RragbENSMUSG00000041658Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006762  Gtr1/RagA G protein
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:1905671 regulation of lysosome organization IMP
 biological_processGO:2000425 regulation of apoptotic cell clearance IMP
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
E3 ubiquitin ligases ubiquitinate target proteins
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain has fewer parts of type microglial cell , abnormal
brain apoptotic cell clearance decreased occurrence , abnormal
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 ZFA:0000445 optic tectum optic tectum apoptotic cell clearance decreased occurrence , abnormal
optic tectum microglial cell morphology , abnormal
optic tectum microglial cell has extra parts of type microglial cell phagolysosome, abnormal
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 ZFA:0001094 whole organism whole organism increased amount , abnormal
whole organism decreased amount , abnormal
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 ZFA:0009077 microglial cell microglial cell lysosome organization process quality , abnormal
microglial cell phagolysosome increased size , abnormal
microglial cell lysosomal protein catabolic process decreased occurrence , abnormal
microglial cell lysosome increased size , abnormal
microglial cell morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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