ENSDARG00000104809


Danio rerio

Features
Gene ID: ENSDARG00000104809
  
Biological name :top1mt
  
Synonyms : DNA topoisomerase I mitochondrial / top1mt
  
Possible biological names infered from orthology : Mus musculus DNA topoisomerase 1, mitochondrial (Top1mt), transcript variant 2, mRNA. / Q8R4U6 / Q969P6
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 42004640
Gene end: 42018243
  
Corresponding Affymetrix probe sets: Dr.11780.1.A1_at (Zebrafish Array)   DrAffx.2.53.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000131182
swissprot - A0A0G2KFV1
ZFIN ID - ZDB-GENE-040624-2
Ensembl - ENSDARG00000104809
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TOP1MTENSGALG00000029572Gallus gallus
 Q969P6ENSG00000184428Homo sapiens
 Q8R4U6ENSMUSG00000000934Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
top1l / DNA topoisomerase I, like / TOP1* / P11387* / Q04750* / DNA topoisomerase I* / DNA topoisomerase 1 *ENSDARG0000007054562
top1 / DNA topoisomerase I / P11387* / Q04750* / DNA topoisomerase 1 *ENSDARG0000008677561
zgc:173742ENSDARG0000000452946


Protein motifs (from Interpro)
Interpro ID Name
 IPR001631  DNA topoisomerase I
 IPR008336  DNA topoisomerase I, DNA binding, eukaryotic-type
 IPR011010  DNA breaking-rejoining enzyme, catalytic core
 IPR013030  DNA topoisomerase I, DNA binding, N-terminal domain 2
 IPR013034  DNA topoisomerase I, DNA binding, N-terminal domain 1
 IPR013499  DNA topoisomerase I, eukaryotic-type
 IPR013500  DNA topoisomerase I, catalytic core, eukaryotic-type
 IPR014711  DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type
 IPR014727  DNA topoisomerase I, catalytic core, alpha/beta subdomain
 IPR018521  DNA topoisomerase I, active site
 IPR025834  Topoisomerase I C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IBA
 biological_processGO:0006265 DNA topological change IBA
 biological_processGO:0006338 chromatin remodeling IBA
 biological_processGO:0007059 chromosome segregation IBA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0031298 replication fork protection complex IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003917 DNA topoisomerase type I activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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