ENSG00000036565


Homo sapiens

Features
Gene ID: ENSG00000036565
  
Biological name :SLC18A1
  
Synonyms : P54219 / SLC18A1 / solute carrier family 18 member A1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p21.3
Gene start: 20144855
Gene end: 20183206
  
Corresponding Affymetrix probe sets: 207074_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428999
Ensembl peptide - ENSP00000428001
Ensembl peptide - ENSP00000429664
Ensembl peptide - ENSP00000265808
Ensembl peptide - ENSP00000276373
Ensembl peptide - ENSP00000371021
Ensembl peptide - ENSP00000387549
Ensembl peptide - ENSP00000413361
NCBI entrez gene - 6570     See in Manteia.
OMIM - 193002
RefSeq - XM_011544627
RefSeq - NM_001135691
RefSeq - NM_001142324
RefSeq - NM_001142325
RefSeq - NM_003053
RefSeq - XM_011544625
RefSeq - XM_011544626
RefSeq Peptide - NP_003044
RefSeq Peptide - NP_001129163
RefSeq Peptide - NP_001135796
RefSeq Peptide - NP_001135797
swissprot - Q96GL6
swissprot - P54219
swissprot - E5RK12
Ensembl - ENSG00000036565
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BX088696.1ENSDARG00000078157Danio rerio
 SLC18A1ENSGALG00000001693Gallus gallus
 Q8R090ENSMUSG00000036330Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q05940 / SLC18A2 / solute carrier family 18 member A2ENSG0000016564662
Q16572 / SLC18A3 / solute carrier family 18 member A3ENSG0000018771437
Q6NT16 / SLC18B1 / solute carrier family 18 member B1ENSG0000014640918


Protein motifs (from Interpro)
Interpro ID Name
 IPR004734  Multidrug resistance protein
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0006837 serotonin transport IEA
 biological_processGO:0006855 drug transmembrane transport IEA
 biological_processGO:0015842 aminergic neurotransmitter loading into synaptic vesicle IBA
 biological_processGO:0015844 monoamine transport TAS
 biological_processGO:0015893 drug transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070083 clathrin-sculpted monoamine transport vesicle membrane TAS
 molecular_functionGO:0008504 monoamine transmembrane transporter activity TAS
 molecular_functionGO:0015222 serotonin transmembrane transporter activity IBA
 molecular_functionGO:0015238 drug transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Na+/Cl- dependent neurotransmitter transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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