Manteia

ENSG00000048649

Homo sapiens

Features

Gene ID:	ENSG00000048649

Biological name :	RSF1

Synonyms :	Q96T23 / remodeling and spacing factor 1 / RSF1

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	11
Strand:	-1
Band:	q14.1
Gene start:	77659996
Gene end:	77821017

Corresponding Affymetrix probe sets:	218166_s_at (Human Genome U133 Plus 2.0 Array) 222540_s_at (Human Genome U133 Plus 2.0 Array) 222541_at (Human Genome U133 Plus 2.0 Array) 223818_s_at (Human Genome U133 Plus 2.0 Array) 229885_at (Human Genome U133 Plus 2.0 Array) 235381_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000436728 Ensembl peptide - ENSP00000434509 Ensembl peptide - ENSP00000436408 Ensembl peptide - ENSP00000311513 Ensembl peptide - ENSP00000408844 Ensembl peptide - ENSP00000432022 Ensembl peptide - ENSP00000433603 NCBI entrez gene - 51773 See in Manteia. OMIM - 608522 RefSeq - XM_017017923 RefSeq - NM_016578 RefSeq - XM_005274051 RefSeq Peptide - NP_057662 swissprot - H7C306 swissprot - H0YCN2 swissprot - H0YEX0 swissprot - Q96T23 swissprot - H0YDG9 swissprot - H0YER1 Ensembl - ENSG00000048649

See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
rsf1b.1	ENSDARG00000068640	Danio rerio
rsf1b.1	ENSDARG00000093503	Danio rerio
RSF1	ENSGALG00000039068	Gallus gallus
Rsf1	ENSMUSG00000035623	Mus musculus

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR001965	Zinc finger, PHD-type
IPR011011	Zinc finger, FYVE/PHD-type
IPR013083	Zinc finger, RING/FYVE/PHD-type
IPR019786	Zinc finger, PHD-type, conserved site
IPR019787	Zinc finger, PHD-finger
IPR028938	Remodeling and spacing factor 1
IPR028942	WHIM1 domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006325	chromatin organization	IEA
biological_process	GO:0006334	nucleosome assembly	IDA
biological_process	GO:0006338	chromatin remodeling	IDA
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006352	DNA-templated transcription, initiation	IDA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
biological_process	GO:0016584	nucleosome positioning	IDA
biological_process	GO:0034080	CENP-A containing nucleosome assembly	TAS
biological_process	GO:0043392	negative regulation of DNA binding	IDA
biological_process	GO:0045892	negative regulation of transcription, DNA-templated	IDA
biological_process	GO:0045893	positive regulation of transcription, DNA-templated	IDA
biological_process	GO:0050434	positive regulation of viral transcription	IDA
cellular_component	GO:0005634	nucleus	IDA
cellular_component	GO:0005654	nucleoplasm	IDA
cellular_component	GO:0031213	RSF complex	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0042393	histone binding	IDA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Deposition of new CENPA-containing nucleosomes at the centromere

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSG00000115163	CENPA / P49450 / centromere protein A	/ complex
ENSG00000153147	O60264 / SMARCA5 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	/ complex
ENSG00000276180	P62805 / HIST1H4I / histone cluster 1 H4 family member i	/ complex
ENSG00000137812	KNL1 / Q8NG31 / kinetochore scaffold 1	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr