ENSG00000049247


Homo sapiens
receptorsignalingregulationUTS2bloodactivityextracellularurotensiniimusclecontractiong-proteincoupledpathwaychemicalsynaptictransmissionpressurevesseldiameterregionspacebindinghormonepeptideligand-bindingreceptorsgalphaqsignalling

Features
Gene ID: ENSG00000049247
  
Biological name :UTS2
  
Synonyms : O95399 / urotensin 2 / UTS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.23
Gene start: 7843083
Gene end: 7853512
  
Corresponding Affymetrix probe sets: 220784_s_at (Human Genome U133 Plus 2.0 Array)   220785_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000054668
Ensembl peptide - ENSP00000355163
Ensembl peptide - ENSP00000366738
NCBI entrez gene - 10911     See in Manteia.
OMIM - 604097
RefSeq - XM_017000119
RefSeq - NM_006786
RefSeq - NM_021995
RefSeq - XM_011540538
RefSeq - XM_017000116
RefSeq - XM_017000117
RefSeq - XM_017000118
RefSeq - XM_011540537
RefSeq Peptide - NP_068835
RefSeq Peptide - NP_006777
swissprot - O95399
swissprot - Q5H8X8
Ensembl - ENSG00000049247
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UTS2ENSGALG00000000556Gallus gallus
 Uts2ENSMUSG00000028963Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001483  Urotensin II


Gene Ontology (GO)
system processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processcell communicationcellular response to stimulusregulation of biological qualityregulation of molecular functionsystem processsystem processcell communicationcell communicationcellular response to stimulucellular response to stimulusregulation of biological quaregulation of biological qualityregulation of molecular funcregulation of molecular function
protein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activity
extracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0008217 regulation of blood pressure TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0097746 regulation of blood vessel diameter IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005179 hormone activity TAS


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000181408 UTS2R / Q9UKP6 / urotensin 2 receptor  / complex / reaction






 

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