ENSG00000181408


Homo sapiens

Features
Gene ID: ENSG00000181408
  
Biological name :UTS2R
  
Synonyms : Q9UKP6 / urotensin 2 receptor / UTS2R
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.3
Gene start: 82374230
Gene end: 82375586
  
Corresponding Affymetrix probe sets: 1553262_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000323516
NCBI entrez gene - 2837     See in Manteia.
OMIM - 600896
RefSeq - NM_018949
RefSeq Peptide - NP_061822
swissprot - Q9UKP6
Ensembl - ENSG00000181408
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UTS2RENSDARG00000009624Danio rerio
 UTS2RENSGALG00000001626Gallus gallus
 Uts2rENSMUSG00000039321Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000670  Urotensin II receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003105 negative regulation of glomerular filtration IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0008015 blood circulation TAS
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0035811 negative regulation of urine volume IEA
 biological_processGO:0035814 negative regulation of renal sodium excretion IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0045777 positive regulation of blood pressure IEA
 biological_processGO:0045907 positive regulation of vasoconstriction IEA
 biological_processGO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 biological_processGO:0097746 regulation of blood vessel diameter IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0001604 urotensin II receptor activity IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000049247 UTS2 / O95399 / urotensin 2  / complex / reaction
 ENSG00000188958 UTS2B / Q765I0 / urotensin 2B  / complex / reaction






 

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