ENSG00000073849


Homo sapiens

Features
Gene ID: ENSG00000073849
  
Biological name :ST6GAL1
  
Synonyms : P15907 / ST6 beta-galactoside alpha-2,6-sialyltransferase 1 / ST6GAL1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q27.3
Gene start: 186930485
Gene end: 187078553
  
Corresponding Affymetrix probe sets: 201998_at (Human Genome U133 Plus 2.0 Array)   214970_s_at (Human Genome U133 Plus 2.0 Array)   214971_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000389337
Ensembl peptide - ENSP00000388928
Ensembl peptide - ENSP00000390793
Ensembl peptide - ENSP00000416163
Ensembl peptide - ENSP00000415886
Ensembl peptide - ENSP00000414504
Ensembl peptide - ENSP00000412821
Ensembl peptide - ENSP00000412221
Ensembl peptide - ENSP00000411518
Ensembl peptide - ENSP00000407631
Ensembl peptide - ENSP00000403063
Ensembl peptide - ENSP00000400547
Ensembl peptide - ENSP00000399525
Ensembl peptide - ENSP00000397273
Ensembl peptide - ENSP00000169298
Ensembl peptide - ENSP00000388789
NCBI entrez gene - 6480     See in Manteia.
OMIM - 109675
RefSeq - XM_017007068
RefSeq - NM_003032
RefSeq - NM_173216
RefSeq - NM_173217
RefSeq - XM_005247719
RefSeq - XM_005247720
RefSeq - XM_006713734
RefSeq - XM_011513085
RefSeq - XM_011513086
RefSeq - XM_017007065
RefSeq - XM_017007066
RefSeq - XM_017007067
RefSeq Peptide - NP_775323
RefSeq Peptide - NP_775324
RefSeq Peptide - NP_001340845
RefSeq Peptide - NP_003023
swissprot - C9JVK7
swissprot - C9JTR0
swissprot - C9JR47
swissprot - C9JPG6
swissprot - C9JKG0
swissprot - C9JI90
swissprot - C9JH16
swissprot - C9JFM4
swissprot - C9JAT4
swissprot - H7C472
swissprot - C9J6X5
swissprot - P15907
swissprot - C9IYS8
swissprot - C9K0R8
Ensembl - ENSG00000073849
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st6gal1ENSDARG00000044514Danio rerio
 ST6GAL1ENSGALG00000005550Gallus gallus
 Q64685ENSMUSG00000022885Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96JF0 / ST6GAL2 / ST6 beta-galactoside alpha-2,6-sialyltransferase 2ENSG0000014405741
Q9BVH7 / ST6GALNAC5 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5ENSG0000011706915
Q9H4F1 / ST6GALNAC4 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4ENSG0000013684015
AL157935.2ENSG0000025752414
Q969X2 / ST6GALNAC6 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6ENSG0000016040813
Q8NDV1 / ST6GALNAC3 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3ENSG0000018400513


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006054 N-acetylneuraminate metabolic process IDA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006959 humoral immune response TAS
 biological_processGO:0009311 oligosaccharide metabolic process IBA
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0018279 protein N-linked glycosylation via asparagine IDA
 biological_processGO:0097503 sialylation IDA
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008373 sialyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Sialic acid metabolism
N-Glycan antennae elongation
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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