ENSG00000136840


Homo sapiens

Features
Gene ID: ENSG00000136840
  
Biological name :ST6GALNAC4
  
Synonyms : Q9H4F1 / ST6GALNAC4 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.11
Gene start: 127907886
Gene end: 127917038
  
Corresponding Affymetrix probe sets: 220937_s_at (Human Genome U133 Plus 2.0 Array)   221551_x_at (Human Genome U133 Plus 2.0 Array)   223285_s_at (Human Genome U133 Plus 2.0 Array)   228163_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000336733
Ensembl peptide - ENSP00000355130
NCBI entrez gene - 27090     See in Manteia.
OMIM - 606378
RefSeq - XM_011518529
RefSeq - NM_175039
RefSeq - NM_175040
RefSeq - XM_011518527
RefSeq Peptide - NP_778204
RefSeq Peptide - NP_778205
swissprot - A6NJX0
swissprot - Q9H4F1
swissprot - A0A024R881
Ensembl - ENSG00000136840
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st6galnac4ENSDARG00000100804Danio rerio
 ST6GALNAC4ENSGALG00000005063Gallus gallus
 St6galnac4ENSMUSG00000079442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NDV1 / ST6GALNAC3 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3ENSG0000018400545
Q9BVH7 / ST6GALNAC5 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5ENSG0000011706940
AL157935.2ENSG0000025752435
Q969X2 / ST6GALNAC6 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6ENSG0000016040829
Q96JF0 / ST6GAL2 / ST6 beta-galactoside alpha-2,6-sialyltransferase 2ENSG0000014405723
P15907 / ST6GAL1 / ST6 beta-galactoside alpha-2,6-sialyltransferase 1ENSG0000007384920


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006664 glycolipid metabolic process TAS
 biological_processGO:0009311 oligosaccharide metabolic process IBA
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0018279 protein N-linked glycosylation via asparagine IBA
 biological_processGO:0097503 sialylation IEA
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity TAS
 molecular_functionGO:0008373 sialyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0047290 (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity TAS


Pathways (from Reactome)
Pathway description
Sialic acid metabolism
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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