ENSG00000079134


Homo sapiens

Features
Gene ID: ENSG00000079134
  
Biological name :THOC1
  
Synonyms : Q96FV9 / THOC1 / THO complex 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: p11.32
Gene start: 214520
Gene end: 268050
  
Corresponding Affymetrix probe sets: 204064_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480460
Ensembl peptide - ENSP00000473499
Ensembl peptide - ENSP00000481599
Ensembl peptide - ENSP00000486359
Ensembl peptide - ENSP00000261600
Ensembl peptide - ENSP00000461943
Ensembl peptide - ENSP00000462757
Ensembl peptide - ENSP00000463965
Ensembl peptide - ENSP00000473276
NCBI entrez gene - 9984     See in Manteia.
OMIM - 606930
RefSeq - XM_017026104
RefSeq - NM_005131
RefSeq - XM_011525772
RefSeq - XM_011525773
RefSeq - XM_011525774
RefSeq - XM_017026103
RefSeq Peptide - NP_005122
swissprot - Q96FV9
swissprot - R4GMN4
swissprot - R4GN58
swissprot - A0A087WY84
swissprot - J3KRD7
swissprot - J3KT14
swissprot - J3QQZ3
swissprot - A0A087WWS1
Ensembl - ENSG00000079134
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thoc1ENSDARG00000088246Danio rerio
 THOC1ENSGALG00000014915Gallus gallus
 Thoc1ENSMUSG00000024287Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR011029  Death-like domain superfamily
 IPR021861  THO complex, subunit THOC1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000018 regulation of DNA recombination IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006396 RNA processing TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0031297 replication fork processing IMP
 biological_processGO:0032784 regulation of DNA-templated transcription, elongation IDA
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation IMP
 biological_processGO:0046784 viral mRNA export from host cell nucleus IDA
 biological_processGO:0048297 negative regulation of isotype switching to IgA isotypes IEA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:2000002 negative regulation of DNA damage checkpoint IMP
 cellular_componentGO:0000346 transcription export complex IDA
 cellular_componentGO:0000347 THO complex IDA
 cellular_componentGO:0000445 THO complex part of transcription export complex IDA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0045171 intercellular bridge IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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