ENSG00000079931


Homo sapiens

Features
Gene ID: ENSG00000079931
  
Biological name :MOXD1
  
Synonyms : monooxygenase DBH like 1 / MOXD1 / Q6UVY6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q23.2
Gene start: 132296055
Gene end: 132401545
  
Corresponding Affymetrix probe sets: 1554474_a_at (Human Genome U133 Plus 2.0 Array)   209708_at (Human Genome U133 Plus 2.0 Array)   243697_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000336998
Ensembl peptide - ENSP00000376202
Ensembl peptide - ENSP00000356940
NCBI entrez gene - 26002     See in Manteia.
OMIM - 609000
RefSeq - XM_017010714
RefSeq - NM_015529
RefSeq - XM_017010715
RefSeq Peptide - NP_056344
swissprot - Q6UVY6
swissprot - A6PVS1
Ensembl - ENSG00000079931
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 moxd1ENSDARG00000031136Danio rerio
 MOXD1ENSGALG00000002911Gallus gallus
 Moxd1ENSMUSG00000020000Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DBH / P09172 / dopamine beta-hydroxylaseENSG0000012345430
PAM / P19021 / peptidylglycine alpha-amidating monooxygenaseENSG0000014573017


Protein motifs (from Interpro)
Interpro ID Name
 IPR000323  Copper type II, ascorbate-dependent monooxygenase, N-terminal
 IPR005018  DOMON domain
 IPR008977  PHM/PNGase F domain superfamily
 IPR014784  Copper type II, ascorbate-dependent monooxygenase-like, C-terminal
 IPR024548  Copper type II ascorbate-dependent monooxygenase, C-terminal
 IPR028460  Tyramine beta-hydroxylase/Dopamine beta-hydroxylase
 IPR028463  DBH-like monooxygenase protein 1
 IPR036939  Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006589 octopamine biosynthetic process IBA
 biological_processGO:0042420 dopamine catabolic process IBA
 biological_processGO:0042421 norepinephrine biosynthetic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030667 secretory granule membrane IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004500 dopamine beta-monooxygenase activity IBA
 molecular_functionGO:0005507 copper ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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