ENSG00000099821


Homo sapiens

Features
Gene ID: ENSG00000099821
  
Biological name :POLRMT
  
Synonyms : O00411 / POLRMT / RNA polymerase mitochondrial
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 617224
Gene end: 633604
  
Corresponding Affymetrix probe sets: 203782_s_at (Human Genome U133 Plus 2.0 Array)   203783_x_at (Human Genome U133 Plus 2.0 Array)   228616_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465759
Ensembl peptide - ENSP00000466504
Ensembl peptide - ENSP00000468658
Ensembl peptide - ENSP00000473524
NCBI entrez gene - 5442     See in Manteia.
OMIM - 601778
RefSeq - XM_005259580
RefSeq - NM_005035
RefSeq Peptide - NP_005026
swissprot - K7EMH3
swissprot - O00411
swissprot - R4GN79
swissprot - K7ESD1
Ensembl - ENSG00000099821
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polrmtENSDARG00000101220Danio rerio
 POLRMTENSGALG00000001377Gallus gallus
 PolrmtENSMUSG00000020329Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002092  DNA-directed RNA polymerase, phage-type
 IPR024075  DNA-directed RNA polymerase, helix hairpin domain superfamily
 IPR029262  DNA-directed RNA polymerase, N-terminal
 IPR037159  DNA-directed RNA polymerase, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006390 mitochondrial transcription IDA
 biological_processGO:0006391 transcription initiation from mitochondrial promoter TAS
 biological_processGO:0007005 mitochondrion organization TAS
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0034245 mitochondrial DNA-directed RNA polymerase complex IBA
 cellular_componentGO:0042645 mitochondrial nucleoid IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
Mitochondrial transcription initiation
Transcriptional activation of mitochondrial biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108064 TFAM / Q00059 / transcription factor A, mitochondrial  / complex / reaction
 ENSG00000162851 TFB2M / Q9H5Q4 / transcription factor B2, mitochondrial  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr