ENSG00000100558


Homo sapiens

Features
Gene ID: ENSG00000100558
  
Biological name :PLEK2
  
Synonyms : pleckstrin 2 / PLEK2 / Q9NYT0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q24.1
Gene start: 67386983
Gene end: 67412200
  
Corresponding Affymetrix probe sets: 218644_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450533
Ensembl peptide - ENSP00000451023
Ensembl peptide - ENSP00000451218
Ensembl peptide - ENSP00000216446
Ensembl peptide - ENSP00000450892
NCBI entrez gene - 26499     See in Manteia.
OMIM - 608007
RefSeq - XM_011536644
RefSeq - NM_016445
RefSeq Peptide - NP_057529
swissprot - H0YJ64
swissprot - H0YJD0
swissprot - G3V337
swissprot - Q9NYT0
swissprot - H0YIZ5
Ensembl - ENSG00000100558
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plek2ENSDARG00000012789Danio rerio
 PLEK2ENSGALG00000009562Gallus gallus
 Plek2ENSMUSG00000021118Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLEK / P08567 / pleckstrinENSG0000011595637


Protein motifs (from Interpro)
Interpro ID Name
 IPR000591  DEP domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily
 IPR037369  Pleckstrin-2, DEP domain
 IPR037370  Pleckstrin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0031346 positive regulation of cell projection organization IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031258 lamellipodium membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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