ENSMUSG00000021118


Mus musculus

Features
Gene ID: ENSMUSG00000021118
  
Biological name :Plek2
  
Synonyms : Pleckstrin-2 / Plek2 / Q9WV52
  
Possible biological names infered from orthology : Q9NYT0
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: C3
Gene start: 78888691
Gene end: 78906964
  
Corresponding Affymetrix probe sets: 10401149 (MoGene1.0st)   1449424_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021544
NCBI entrez gene - 27260     See in Manteia.
MGI - MGI:1351466
RefSeq - NM_013738
RefSeq - XM_006515934
RefSeq Peptide - NP_038766
swissprot - Q9WV52
Ensembl - ENSMUSG00000021118
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plek2ENSDARG00000012789Danio rerio
 PLEK2ENSGALG00000009562Gallus gallus
 PLEK2ENSG00000100558Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plek / Q9JHK5 / pleckstrin / P08567*ENSMUSG0000002012036


Protein motifs (from Interpro)
Interpro ID Name
 IPR000591  DEP domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily
 IPR037369  Pleckstrin-2, DEP domain
 IPR037370  Pleckstrin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization IMP
 biological_processGO:0031346 positive regulation of cell projection organization IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031258 lamellipodium membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IDA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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