ENSG00000106410


Homo sapiens

Features
Gene ID: ENSG00000106410
  
Biological name :NOBOX
  
Synonyms : NOBOX / NOBOX oogenesis homeobox / O60393
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q35
Gene start: 144397240
Gene end: 144410227
  
Corresponding Affymetrix probe sets: 234519_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000495343
Ensembl peptide - ENSP00000496732
Ensembl peptide - ENSP00000419457
Ensembl peptide - ENSP00000419565
NCBI entrez gene - 135935     See in Manteia.
OMIM - 610934
RefSeq - NM_001080413
RefSeq - XM_017011742
RefSeq Peptide - NP_001073882
swissprot - O60393
Ensembl - ENSG00000106410
  
Related genetic diseases (OMIM): 611548 - Premature ovarian failure 5, 611548

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000043916Gallus gallus
 NoboxENSMUSG00000029736Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0048477 oogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000006 Autosomal dominant inheritance "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in heterozygotes. In the context of medical genetics, an autosomal dominant disorder is caused when a single copy of the mutant allele is present. Males and females are affected equally, and can both transmit the disorder with a risk of 50% for each child of inheriting the mutant allele." [HPO:curators]
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 HP:0000786 Primary amenorrhea 
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 HP:0000869 Secondary amenorrhea 
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 HP:0008209 Premature ovarian failure 
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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